Desipramine hydrochloride

Also known as: Desipramine HCl, Desmethylimipramine hydrochloride, Norpramin, Pertofrane, 10,11-Dihydro-5-(3-methylaminopropyl)-5H-dibenz[b,f]azepine hydrochloride, 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride

Desipramine hydrochloride (CAS 50-47-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C18H22N2 and a molecular weight of 266.38100 g/mol. Key properties include a melting point of 212°C, a boiling point of 407.4ºC at 760 mmHg, a density of 1.047 g/cm3 and a flash point of 160.5ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 50-47-5
Jingsj CID: J-1991987-0
Molecular Formula: C₁₈H₂₂N₂
Molecular Weight: 266.38100 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	212°C
Boiling Point	407.4ºC at 760 mmHg
Density	1.047 g/cm3
Flash Point	160.5ºC
Exact Mass	266.17800
PSA	15.27000
LogP	3.98870
Refractive Index	1.5200 (estimate)

Activity & Biological Data

Target	Norepinephrine Reuptake Receptor[1]
Additional Information	[1]. Garcia AS, et al. Autoreceptor-mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment. J Neurochem. 2004 Nov;91(3):683-93. [2]. Taranto-Montemurro L, et al. Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation. Eur Respir J. 2016 Nov;48(5):1340-1350.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Desipramine hydrochloride?

The CAS number of Desipramine hydrochloride is 50-47-5.

What are the molecular formula and molecular weight of Desipramine hydrochloride?

Desipramine hydrochloride has molecular formula C18H22N2 and molecular weight 266.38100 g/mol.

What are the upstream and downstream products of Desipramine hydrochloride?

For Desipramine hydrochloride, Upstream Products: Imipramine, Imipramine hydrochloride, Desipramine hydrochloride; Downstream Products: Imipramine, Chlorodimethylsilane, Lofepramine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Desipramine hydrochloride (CAS 50-47-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1991987-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.