Lofepramine
Also known as: 1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz(Z)[b,f]azepin-5-yl)propyl]methylamino]ethanone, 1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]ethanone, 1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone, 4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl-methylamino]acetophenone, Amplit, Gamanil, LOFEPRAMINE, Leo 640, lofepramine
Lofepramine (CAS 23047-25-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H27ClN2O and a molecular weight of 418.95800 g/mol. Key properties include a boiling point of 575ºC at 760mmHg, a density of 1.173g/cm3 and a flash point of 301.6ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 23047-25-8
- Jingsj CID
- J-1985305-5
- Molecular Formula
- C26H27ClN2O
- Molecular Weight
- 418.95800 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 575ºC at 760mmHg |
|---|---|
| Density | 1.173g/cm3 |
| Flash Point | 301.6ºC |
| Exact Mass | 418.18100 |
| PSA | 23.55000 |
| LogP | 5.84650 |
| Vapor Pressure | 3.17E-13mmHg at 25°C |
| Refractive Index | 1.607 |
Activity & Biological Data
| Additional Information | [1]. Lancaster SG, et al. Lofepramine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs. 1989 Feb;37(2):123-40. |
|---|
Frequently Asked Questions
What is the CAS number of Lofepramine?
The CAS number of Lofepramine is 23047-25-8.
What are the molecular formula and molecular weight of Lofepramine?
Lofepramine has molecular formula C26H27ClN2O and molecular weight 418.95800 g/mol.
What are the upstream and downstream products of Lofepramine?
For Lofepramine, Upstream Products: Desipramine hydrochloride, 2-Bromo-4'-chloroacetophenone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Lofepramine (CAS 23047-25-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1985305-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.