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(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid

Also known as: (+) -Mosher's acid, (+)-MTPA, Mosher's acid, R-Mosher's acid, (2R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid, (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid, (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid, (R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid, Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (R)-

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid (CAS 20445-31-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C10H9F3O3 and a molecular weight of 234.172 g/mol. Key properties include a melting point of 46-49ºC, a boiling point of 287.2±0.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 134.2±27.3 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
20445-31-2
Jingsj CID
J-17290-7
Molecular Formula
C10H9F3O3
Molecular Weight
234.172 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point46-49ºC
Boiling Point287.2±0.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point134.2±27.3 °C
Exact Mass234.050385
PSA46.53000
LogP3.79
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.470
Storage Conditions2-8℃

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2918990090
Summary2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid?

The CAS number of (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid is 20445-31-2.

What are the molecular formula and molecular weight of (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid?

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid has molecular formula C10H9F3O3 and molecular weight 234.172 g/mol.

Is (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid hazardous?

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid?

For (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, Upstream Products: (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, 2,2,2-Trifluoroacetophenone; Downstream Products: (±)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid (CAS 20445-31-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-17290-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.