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(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid

Also known as: Mosher's acid, (-)-Mosher's acid, (S)-(-)-MTPA, (S)-(-)-Mosher's acid, (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid [Optical resolving], (-)-MTPA, (2S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid, S-(-)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid

(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid (CAS 17257-71-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C10H9F3O3 and a molecular weight of 234.172 g/mol. Key properties include a melting point of 46-49ºC, a boiling point of 287.2±0.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 134.2±27.3 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
17257-71-5
Jingsj CID
J-17291-8
Molecular Formula
C10H9F3O3
Molecular Weight
234.172 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point46-49ºC
Boiling Point287.2±0.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point134.2±27.3 °C
Exact Mass234.050385
PSA46.53000
LogP3.79
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.470

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2918990090
Summary2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid?

The CAS number of (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid is 17257-71-5.

What are the molecular formula and molecular weight of (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid?

(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid has molecular formula C10H9F3O3 and molecular weight 234.172 g/mol.

Is (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid hazardous?

(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid?

For (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, Upstream Products: 2,2,2-Trifluoroacetophenone, (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid; Downstream Products: (S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 1,3-Diisopropylurea.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid (CAS 17257-71-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-17291-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.