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2,2,2-Trifluoroacetophenone

Also known as: Trifluoroacetophenone, Phenyl trifluoromethyl ketone, 2,2,2-Trifluoro-1-phenylethanone, 1-Phenyl-2,2,2-trifluoroethanone, α,α,α-Trifluoroacetophenone, NSC 42752, TRIFLUOROACETYLBENZENE, 2,2,2-trifluroacetophenone

2,2,2-Trifluoroacetophenone (CAS 434-45-7) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H5F3O and a molecular weight of 174.120 g/mol. Key properties include a melting point of -40 °C, a boiling point of 165.5±0.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 41.7±0.0 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
434-45-7
Jingsj CID
J-21167-6
Molecular Formula
C8H5F3O
Molecular Weight
174.120 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point-40 °C
Boiling Point165.5±0.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point41.7±0.0 °C
Exact Mass174.029251
PSA17.07000
LogP2.15
Vapor Pressure1.9±0.3 mmHg at 25°C
Refractive Index1.448
Storage ConditionsFlammables area
Additional PropertyPRACTICALLY INSOLUBLE

GHS Safety & Compliance

Flammable / IrritantSignal word: Warning
  • H226 — Flammable liquid and vapour
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2914700090
SummaryHS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2,2,2-Trifluoroacetophenone?

The CAS number of 2,2,2-Trifluoroacetophenone is 434-45-7.

What are the molecular formula and molecular weight of 2,2,2-Trifluoroacetophenone?

2,2,2-Trifluoroacetophenone has molecular formula C8H5F3O and molecular weight 174.120 g/mol.

Is 2,2,2-Trifluoroacetophenone hazardous?

2,2,2-Trifluoroacetophenone has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 2,2,2-Trifluoroacetophenone?

For 2,2,2-Trifluoroacetophenone, Upstream Products: Methyl benzoate, Trifluoromethane, Trifluoroacetonitrile; Downstream Products: 1-(3-Chlorophenyl)-2,2,2-trifluoroethanone, 4'-chloro-2,2,2-trifluoroacetophenone, (S)-(+)-α-(Trifluoromethyl)benzyl alcohol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2,2,2-Trifluoroacetophenone (CAS 434-45-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-21167-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.