Chlorogenic acid

Also known as: 3-O-Caffeoylquinic acid, 3-Caffeoylquinic acid, Caffeoyl quinic acid, 3-(3,4-Dihydroxycinnamoyl)quinic acid, Heriguard, Chlorogenate, Chlorogenic acid hydrate, (1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxycyclohexane-1-carboxylic acid

Chlorogenic acid (CAS 327-97-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C16H18O9 and a molecular weight of 354.309 g/mol. Key properties include a melting point of 210 °C (dec.)(lit.), a boiling point of 665.0±55.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 245.5±25.0 °C. It is listed by 2 suppliers, 1 of which publish reference prices, from 4.00 to 280.00 CNY. Record last updated Aug 21, 2026.

CAS No.: 327-97-9
Jingsj CID: J-45128-0
Molecular Formula: C₁₆H₁₈O₉
Molecular Weight: 354.309 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Jingkang In Stock	分析标准品 20mg	¥80.00	$0.6 /mgBest ¥4.00/mg CNY	CN China MOQ 20mg	Visit Website
Jingkang In Stock	98% 5g	¥228.00	$6.82 /g ¥45.60/g CNY	CN China MOQ 5g	Visit Website
Jingkang In Stock	98% 1g	¥280.00	$41.9 /g ¥280.00/g CNY	CN China MOQ 1g	Visit Website
Jingheng Materials Made to Order	98% 25g	-	-	CN China MOQ 25g	Visit Website
Jingheng Materials Made to Order	98% 100g	-	-	CN China MOQ 100g	Visit Website
Jingheng Materials Made to Order	98% 500g	-	-	CN China MOQ 500g	Visit Website

Physicochemical Properties

Melting Point	210 °C (dec.)(lit.)
Boiling Point	665.0±55.0 °C at 760 mmHg
Density	1.7±0.1 g/cm3
Flash Point	245.5±25.0 °C
Exact Mass	354.095093
PSA	164.75000
LogP	-0.36
Vapor Pressure	0.0±2.1 mmHg at 25°C
Refractive Index	1.690
Additional Property	SOLUBLE IN HOT WATER

Activity & Biological Data

Additional Information	[1]. Park JJ, et al. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway. Cell Oncol (Dordr). 2015 Jan 6. [2]. Park SH, et al. IRAK4 as a Molecular Target in the Amelioration of Innate Immunity-Related Endotoxic Shock and Acute Liver Injury by Chlorogenic Acid. J Immunol. 2015 Feb 1;194(3):1122-30. [3]. Kang JW, et al. Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats. Biomol Ther (Seoul). 2014 Sep;22(5):420-5.

Additional Information

[1]. Park JJ, et al. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway. Cell Oncol (Dordr). 2015 Jan 6. [2]. Park SH, et al. IRAK4 as a Molecular Target in the Amelioration of Innate Immunity-Related Endotoxic Shock and Acute Liver Injury by Chlorogenic Acid. J Immunol. 2015 Feb 1;194(3):1122-30. [3]. Kang JW, et al. Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats. Biomol Ther (Seoul). 2014 Sep;22(5):420-5.

Frequently Asked Questions

What is the CAS number of Chlorogenic acid?

The CAS number of Chlorogenic acid is 327-97-9.

What are the molecular formula and molecular weight of Chlorogenic acid?

Chlorogenic acid has molecular formula C16H18O9 and molecular weight 354.309 g/mol.

Which suppliers offer Chlorogenic acid?

2 supplier(s) listed; reference unit price ¥4.00–280.00 /mg.

What are the upstream and downstream products of Chlorogenic acid?

For Chlorogenic acid, Downstream Products: Caffeic acid, D-(-)-Quinic acid, Cryptochlorogenic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Chlorogenic acid (CAS 327-97-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-45128-0 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.