Chlorpromazine hydrochloride

Also known as: Chlorpromazine HCl, CPZ, Largactil, Thorazine, 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine hydrochloride, Chlorpromazine monohydrochloride, Aminazin Hydrochloride, Ampliactil, Chloractil, Chlorazin, Hibernal, Megaphen, Plegomazin, Propaphen, Taroctyl

Chlorpromazine hydrochloride (CAS 69-09-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C17H20Cl2N2S and a molecular weight of 355.33 g/mol. Key properties include a melting point of 192-196°C, a boiling point of 450.1ºC at 760 mmHg, a density of 1.077 g/cm3 (15 C) and a flash point of 9 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H330 — Fatal if inhaled. It is listed by 1 supplier, from 3.76 to 4.40 CNY. Record last updated Aug 21, 2026.

CAS No.: 69-09-0
Jingsj CID: J-29680-5
Molecular Formula: C₁₇H₂₀Cl₂N₂S
Molecular Weight: 355.33 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Maikuo Made to Order	98% 500g	¥1,880.00	$0.56 /gBest ¥3.76/g CNY	CN China MOQ 500g	View Product
Maikuo Made to Order	98% 100g	¥400.00	$0.6 /g ¥4.00/g CNY	CN China MOQ 100g	View Product
Maikuo Made to Order	98% 25g	¥110.00	$0.66 /g ¥4.40/g CNY	CN China MOQ 25g	View Product

Physicochemical Properties

Melting Point	192-196°C
Boiling Point	450.1ºC at 760 mmHg
Density	1.077 g/cm3 (15 C)
Flash Point	9 °C
Exact Mass	354.072418
PSA	31.78000
LogP	5.76140
Refractive Index	1.4436 (20ºC)
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. Air and light sesnsitive.
Additional Property	>=10 g/100 mL at 24 ºC
SMILES	CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl
InChIKey	FBSMERQALIEGJT-UHFFFAOYSA-N
InChI	1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed
H330 — Fatal if inhaled

Activity & Biological Data

Target	Ki: 363 nM (dopamine D2 receptor), 8.3 nM (5-HT2A receptor)[4]
Additional Information	[1]. Lee SJ, et al. Mechanism of inhibition by chlorpromazine of the human pain threshold sodium channel, Nav1.7. Neurosci Lett. 2017 Feb 3;639:1-7 [2]. Kale OE, et al. Amlodipine, an L-type calcium channel blocker, protects against chlorpromazine-induced neurobehavioural deficits in mice. Fundam Clin Pharmacol. 2017 Jan 19 [3]. Sampaio LR, et al. Electroencephalographic study of chlorpromazine alone or combined with alpha-lipoic acid in a model of schizophrenia induced by ketamine in rats. J Psychiatr Res. 2017 Mar;86:73-82 [4]. Suzuki H, et al. Comparison of the anti-dopamine D? and anti-serotonin 5-HT(2A) activities of chlorpromazine, bromperidol, haloperidol and second-generation antipsychotics parent compounds and metabolites thereof. J Psychopharmacol. 2013 Apr;27(4):396-400 [5]. Thomas, D., et al. The antipsychotic drug chlorpromazine inhibits HERG potassium channels. Br J Pharmacol, 2003. 139(3): p. 567-74.

Target

Ki: 363 nM (dopamine D2 receptor), 8.3 nM (5-HT2A receptor)[4]

Additional Information

[1]. Lee SJ, et al. Mechanism of inhibition by chlorpromazine of the human pain threshold sodium channel, Nav1.7. Neurosci Lett. 2017 Feb 3;639:1-7 [2]. Kale OE, et al. Amlodipine, an L-type calcium channel blocker, protects against chlorpromazine-induced neurobehavioural deficits in mice. Fundam Clin Pharmacol. 2017 Jan 19 [3]. Sampaio LR, et al. Electroencephalographic study of chlorpromazine alone or combined with alpha-lipoic acid in a model of schizophrenia induced by ketamine in rats. J Psychiatr Res. 2017 Mar;86:73-82 [4]. Suzuki H, et al. Comparison of the anti-dopamine D? and anti-serotonin 5-HT(2A) activities of chlorpromazine, bromperidol, haloperidol and second-generation antipsychotics parent compounds and metabolites thereof. J Psychopharmacol. 2013 Apr;27(4):396-400 [5]. Thomas, D., et al. The antipsychotic drug chlorpromazine inhibits HERG potassium channels. Br J Pharmacol, 2003. 139(3): p. 567-74.

Customs & Trade Information

HS Code	2934300000
Summary	2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Chlorpromazine hydrochloride?

The CAS number of Chlorpromazine hydrochloride is 69-09-0.

What are the molecular formula and molecular weight of Chlorpromazine hydrochloride?

Chlorpromazine hydrochloride has molecular formula C17H20Cl2N2S and molecular weight 355.33 g/mol.

Which suppliers offer Chlorpromazine hydrochloride?

1 supplier(s) listed; reference unit price ¥3.76–4.40 /g.

Is Chlorpromazine hydrochloride hazardous?

Chlorpromazine hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H330 — Fatal if inhaled.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Chlorpromazine hydrochloride (CAS 69-09-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-29680-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.