Methyl L-pyroglutamate
Also known as: Methyl (S)-5-oxopyrrolidine-2-carboxylate, L-Pyroglutamic acid methyl ester, Methyl (S)-(+)-2-pyrrolidone-5-carboxylate, Methyl 5-oxo-L-prolinate, (S)-5-Oxopyrrolidine-2-carboxylic acid methyl ester, 2-Pyrrolidone-5-carboxylic acid methyl ester, H-PGLU-OME, L-PYR-OME, pGlu-OMe, MFCD00080931, EINECS 225-567-3
Methyl L-pyroglutamate (CAS 4931-66-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C6H9NO3 and a molecular weight of 143.141 g/mol. Key properties include a boiling point of 304.7±35.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 138.1±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 4931-66-2
- Jingsj CID
- J-6138-1
- Molecular Formula
- C6H9NO3
- Molecular Weight
- 143.141 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 304.7±35.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 138.1±25.9 °C |
| Exact Mass | 143.058243 |
| PSA | 55.40000 |
| LogP | -1.92 |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
| Refractive Index | 1.465 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Kim KH, et al. 1-Carbomethoxy-β-Carboline, Derived from Portulaca oleracea L., Ameliorates LPS-Mediated Inflammatory Response Associated with MAPK Signaling and Nuclear Translocation of NF-κB.Molecules. 2019 Nov 7;24(22). pii: E4042. |
|---|
Customs & Trade Information
| HS Code | 2933790090 |
|---|---|
| Summary | 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Methyl L-pyroglutamate?
The CAS number of Methyl L-pyroglutamate is 4931-66-2.
What are the molecular formula and molecular weight of Methyl L-pyroglutamate?
Methyl L-pyroglutamate has molecular formula C6H9NO3 and molecular weight 143.141 g/mol.
Is Methyl L-pyroglutamate hazardous?
Methyl L-pyroglutamate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Methyl L-pyroglutamate?
For Methyl L-pyroglutamate, Upstream Products: L-Pyroglutamic acid, Methanol, DL-Pyroglutamic acid; Downstream Products: (5S)-5-[[[(tert-Butyl)dimethylsilyl]oxy]methyl]pyrrolidin-2-one, Methyl (2S)-1-methyl-5-oxopyrrolidine-2-carboxylate, (2S,4R)-1-(tert-Butoxycarbonyl)-4-methylpyrrolidine-2-carboxylic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Methyl L-pyroglutamate (CAS 4931-66-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-6138-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.