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Naltrexone hydrochloride

Also known as: Naltrexone hydrochloride, Naltrexone HCl, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, (5α)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-one hydrochloride (1:1), (1S,5R,13R,17S)-4-(Cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-one hydrochloride, (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-one hydrochloride, (1S,5R,13R,17S)-4-(cyclopropylméthyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadéca-7(18),8,10-trién-14-one chlorhydrate, (1S,5R,13R,17S)-4-(Cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-onhydrochlorid, Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5α)-, hydrochloride (1:1), N-Cyclopropylmethyl-14-hydroxydihydromorphinone hydrochloride, N-CYCLOPROPYLMETHYL-14-HYDROXYDI-HYDROMORPHINONE HYDROCHLORIDE, EN 1639A, NIH 8503, Antaxone, Depade, Nalorex, ReVia, Trexan, Celupan

Naltrexone hydrochloride (CAS 16676-29-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C20H24ClNO4 and a molecular weight of 377.862 g/mol. Key properties include a melting point of 274-2760C, a boiling point of 558.1ºC at 760 mmHg, a density of 1.47 g/cm3 and a flash point of 291.4ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
16676-29-2
Jingsj CID
J-48225-7
Molecular Formula
C20H24ClNO4
Molecular Weight
377.862 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point274-2760C
Boiling Point558.1ºC at 760 mmHg
Density1.47 g/cm3
Flash Point291.4ºC
Exact Mass377.139374
PSA70.00000
LogP2.26530
Vapor Pressure2.71E-13mmHg at 25°C
Storage Conditions2-8°C
Additional PropertyH2O: 50 mg/mL, clear, colorless

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Frequently Asked Questions

What is the CAS number of Naltrexone hydrochloride?

The CAS number of Naltrexone hydrochloride is 16676-29-2.

What are the molecular formula and molecular weight of Naltrexone hydrochloride?

Naltrexone hydrochloride has molecular formula C20H24ClNO4 and molecular weight 377.862 g/mol.

Is Naltrexone hydrochloride hazardous?

Naltrexone hydrochloride has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Naltrexone hydrochloride?

For Naltrexone hydrochloride, Upstream Products: Noroxymorphone, Cyclopropanecarboxaldehyde, naltrexone; Downstream Products: Nor-binaltorphimine dihydrochloride, Naltrindole hydrochloride, naltrexone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Naltrexone hydrochloride (CAS 16676-29-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48225-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.