Tangeretin

Also known as: 4',5,6,7,8-Pentamethoxyflavone, 5,6,7,8,4'-Pentamethoxyflavone, 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-5,6,7,8-tetramethoxy-, 5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one, Ponkanetin, Tangeritin, Tangeritine, NSC 53909, NSC 618905, MFCD00017438

Tangeretin (CAS 481-53-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H20O7 and a molecular weight of 372.369 g/mol. Key properties include a melting point of 155 °C, a boiling point of 565.3±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 248.4±30.2 °C. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 481-53-8
Jingsj CID: J-38025-6
Molecular Formula: C₂₀H₂₀O₇
Molecular Weight: 372.369 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	155 °C
Boiling Point	565.3±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	248.4±30.2 °C
Exact Mass	372.120911
PSA	76.36000
LogP	2.66
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.566
Additional Property	insoluble

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300

Activity & Biological Data

Additional Information	[1]. Zhang X, et al. Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Oncol Rep. 2015 Jul;34(1):302-10. [2]. Xu JJ, et al. Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. J Agric Food Chem. 2015 Nov 4;63(43):9520-7. [3]. Hagenlocher Y, et al. Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. Eur J Nutr. 2016 Mar 28.

Additional Information

[1]. Zhang X, et al. Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Oncol Rep. 2015 Jul;34(1):302-10. [2]. Xu JJ, et al. Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. J Agric Food Chem. 2015 Nov 4;63(43):9520-7. [3]. Hagenlocher Y, et al. Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. Eur J Nutr. 2016 Mar 28.

Frequently Asked Questions

What is the CAS number of Tangeretin?

The CAS number of Tangeretin is 481-53-8.

What are the molecular formula and molecular weight of Tangeretin?

Tangeretin has molecular formula C20H20O7 and molecular weight 372.369 g/mol.

Is Tangeretin hazardous?

Tangeretin has GHS signal word Danger and hazard statements H300.

What are the upstream and downstream products of Tangeretin?

For Tangeretin, Upstream Products: iodomethane, Dimethyl sulfate, 4-(Benzyloxy)benzaldehyde; Downstream Products: Gardenin B, Salvigenin, Artemetin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tangeretin (CAS 481-53-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38025-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.