Meclizine dihydrochloride
Also known as: Meclizine hydrochloride, Meclozine dihydrochloride, Meclozine hydrochloride, 1-[(4-Chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine dihydrochloride, 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)piperazine dihydrochloride, Ancolan dihydrochloride, Bonamine, Diadril, Navidoxine, Postafen, Postafene dihydrochloride, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride, NSC 28728
Meclizine dihydrochloride (CAS 1104-22-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C25H29Cl3N2 and a molecular weight of 463.870 g/mol. Key properties include a melting point of 212 °C, a boiling point of 495.3ºC at 760mmHg, a density of 1.159g/cm3 and a flash point of 253.3ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H361 — Suspected of damaging fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1104-22-9
- Jingsj CID
- J-37934-0
- Molecular Formula
- C25H29Cl3N2
- Molecular Weight
- 463.870 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 212 °C |
|---|---|
| Boiling Point | 495.3ºC at 760mmHg |
| Density | 1.159g/cm3 |
| Flash Point | 253.3ºC |
| Exact Mass | 462.139618 |
| PSA | 6.48000 |
| LogP | 7.03540 |
| Vapor Pressure | 6E-10mmHg at 25°C |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H361 — Suspected of damaging fertility or the unborn child
Activity & Biological Data
| Additional Information | [1]. King, C.T., S.A. Weaver, and S.A. Narrod, Antihistamines and Teratogenicity in the Rat. J Pharmacol Exp Ther, 1965. 147: p. 391-8. [2]. Huang, W., et al., Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR. Mol Endocrinol, 2004. 18(10): p. 2402-8. |
|---|
Customs & Trade Information
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Meclizine dihydrochloride?
The CAS number of Meclizine dihydrochloride is 1104-22-9.
What are the molecular formula and molecular weight of Meclizine dihydrochloride?
Meclizine dihydrochloride has molecular formula C25H29Cl3N2 and molecular weight 463.870 g/mol.
Is Meclizine dihydrochloride hazardous?
Meclizine dihydrochloride has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H361 — Suspected of damaging fertility or the unborn child.
What are the upstream and downstream products of Meclizine dihydrochloride?
For Meclizine dihydrochloride, Upstream Products: 3-Methylbenzyl chloride, 1-[(4-Chlorophenyl)(phenyl)methyl]piperazine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Meclizine dihydrochloride (CAS 1104-22-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37934-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.