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2-Amino-4-(trifluoromethyl)pyridine

Also known as: 4-(Trifluoromethyl)pyridin-2-amine, 4-Trifluoromethyl-2-pyridinamine, 4-Trifluoromethyl-pyridin-2-ylamine, 2-Pyridinamine, 4-(trifluoromethyl)-, MFCD00077455

2-Amino-4-(trifluoromethyl)pyridine (CAS 106447-97-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H5F3N2 and a molecular weight of 162.11 g/mol. Key properties include a melting point of 70-74 °C, a boiling point of 221.3±40.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 87.7±27.3 °C. It is classified under GHS with signal word Danger and hazard statements H300, H315 — Causes skin irritation and H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
106447-97-6
Jingsj CID
J-34398-6
Molecular Formula
C6H5F3N2
Molecular Weight
162.11 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point70-74 °C
Boiling Point221.3±40.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point87.7±27.3 °C
Exact Mass162.040482
PSA38.91000
LogP2.07
Vapor Pressure0.1±0.4 mmHg at 25°C
Refractive Index1.479

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H300
  • H315 — Causes skin irritation
  • H317 — May cause an allergic skin reaction
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Amino-4-(trifluoromethyl)pyridine?

The CAS number of 2-Amino-4-(trifluoromethyl)pyridine is 106447-97-6.

What are the molecular formula and molecular weight of 2-Amino-4-(trifluoromethyl)pyridine?

2-Amino-4-(trifluoromethyl)pyridine has molecular formula C6H5F3N2 and molecular weight 162.11 g/mol.

Is 2-Amino-4-(trifluoromethyl)pyridine hazardous?

2-Amino-4-(trifluoromethyl)pyridine has GHS signal word Danger and hazard statements H300; H315 — Causes skin irritation; H317 — May cause an allergic skin reaction.

What are the upstream and downstream products of 2-Amino-4-(trifluoromethyl)pyridine?

For 2-Amino-4-(trifluoromethyl)pyridine, Upstream Products: 5-Bromo-4-(trifluoromethyl)pyridin-2-amine, Bis(pinacolato)diboron, 2,6-Dichloro-4-(trifluoromethyl)pyridine; Downstream Products: 2-Hydroxy-4-(trifluoromethyl)pyridine, 5-Bromo-4-(trifluoromethyl)pyridin-2-amine, Buparlisib hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Amino-4-(trifluoromethyl)pyridine (CAS 106447-97-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-34398-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.