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2-Hydroxy-4-(trifluoromethyl)pyridine

Also known as: 4-(Trifluoromethyl)pyridin-2(1H)-one, 4-(Trifluoromethyl)-2(1H)-pyridinone, 4-(Trifluoromethyl)-2-pyridone, 4-(Trifluoromethyl)-2-pyridinone, 4-(Trifluoromethyl)pyridin-2-ol, 4-Trifluoromethyl-2(1H)pyridinone, 4-(trifluoromethyl)-1H-pyridin-2-one, 2(1H)-Pyridinone, 4-(trifluoromethyl)-, MFCD00153195

2-Hydroxy-4-(trifluoromethyl)pyridine (CAS 50650-59-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H4F3NO and a molecular weight of 163.097 g/mol. Key properties include a melting point of 161-165 °C(lit.), a boiling point of 302.6±37.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 136.8±26.5 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
50650-59-4
Jingsj CID
J-1012412-6
Molecular Formula
C6H4F3NO
Molecular Weight
163.097 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point161-165 °C(lit.)
Boiling Point302.6±37.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point136.8±26.5 °C
Exact Mass163.024506
PSA33.12000
LogP0.82
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.457

GHS Safety & Compliance

Corrosion / IrritantSignal word: Danger
  • H302 — Harmful if swallowed
  • H318 — Causes serious eye damage

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Hydroxy-4-(trifluoromethyl)pyridine?

The CAS number of 2-Hydroxy-4-(trifluoromethyl)pyridine is 50650-59-4.

What are the molecular formula and molecular weight of 2-Hydroxy-4-(trifluoromethyl)pyridine?

2-Hydroxy-4-(trifluoromethyl)pyridine has molecular formula C6H4F3NO and molecular weight 163.097 g/mol.

Is 2-Hydroxy-4-(trifluoromethyl)pyridine hazardous?

2-Hydroxy-4-(trifluoromethyl)pyridine has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H318 — Causes serious eye damage.

What are the upstream and downstream products of 2-Hydroxy-4-(trifluoromethyl)pyridine?

For 2-Hydroxy-4-(trifluoromethyl)pyridine, Upstream Products: (E)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one, Chloroacetonitrile, 2-Amino-4-(trifluoromethyl)pyridine; Downstream Products: 2-Chloro-4-(trifluoromethyl)pyridine, 5-Bromo-4-(trifluoromethyl)pyridin-2-ol, 4-(Trifluoromethyl)pyridine-2-thiol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Hydroxy-4-(trifluoromethyl)pyridine (CAS 50650-59-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1012412-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.