(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
Also known as: N-Boc-trans-4-hydroxy-D-proline, Boc-trans-4-hydroxy-D-proline, Boc-D-trans-Hyp-OH, N-Boc-trans-D-Hyp-OH, (2R,4S)-N-Boc-4-hydroxy-D-proline, (2R,4S)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, (4S)-4-Hydroxy-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline, 1-tert-Butoxycarbonyl-(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid, MFCD01861341
(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid (CAS 147266-92-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C10H17NO5 and a molecular weight of 231.246 g/mol. Key properties include a melting point of 123ºC, a boiling point of 390.9±42.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 190.2±27.9 °C. It is classified under GHS with signal word Warning and hazard statements H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 147266-92-0
- Jingsj CID
- J-31765-7
- Molecular Formula
- C10H17NO5
- Molecular Weight
- 231.246 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 123ºC |
|---|---|
| Boiling Point | 390.9±42.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 190.2±27.9 °C |
| Exact Mass | 231.110672 |
| PSA | 87.07000 |
| LogP | -0.71 |
| Vapor Pressure | 0.0±2.0 mmHg at 25°C |
| Refractive Index | 1.531 |
GHS Safety & Compliance
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | Non-cleavable |
|---|---|
| Additional Information | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid?
The CAS number of (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid is 147266-92-0.
What are the molecular formula and molecular weight of (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid?
(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid has molecular formula C10H17NO5 and molecular weight 231.246 g/mol.
Is (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid hazardous?
(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid has GHS signal word Warning and hazard statements H319 — Causes serious eye irritation.
What are the upstream and downstream products of (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid?
For (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid, Upstream Products: Di-tert-butyl dicarbonate, L-Hydroxyproline, trans-4-Hydroxy-D-proline; Downstream Products: tert-Butyl (2R,4S)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid (CAS 147266-92-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-31765-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.