L-Hydroxyproline
Also known as: 4-Hydroxy-L-proline, trans-4-Hydroxy-L-proline, Hydroxyproline, 4-Hydroxyproline, (-)-(2S,4R)-4-HYDROXYPROLINE, (2S,4R)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, (2S,4R)-4-hydroxyproline, (4R)-4-Hydroxy-L-proline, trans-4-hydroxyproline, L-trans-4-hydroxyproline, 4-Hydroxy-2-pyrrolidinecarboxylic acid, EINECS 200-091-9, MFCD00064320
L-Hydroxyproline (CAS 51-35-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H9NO3 and a molecular weight of 131.130 g/mol. Key properties include a melting point of 273 °C (dec.)(lit.), a boiling point of 355.2±42.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 168.6±27.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 51-35-4
- Jingsj CID
- J-1072585-6
- Molecular Formula
- C5H9NO3
- Molecular Weight
- 131.130 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 273 °C (dec.)(lit.) |
|---|---|
| Boiling Point | 355.2±42.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 168.6±27.9 °C |
| Exact Mass | 131.058243 |
| PSA | 69.56000 |
| LogP | -1.84 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.540 |
| Additional Property | 357.8 g/L (20 º C) |
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Yi Y, et al. Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli . BMC Biotechnol. 2014 May 19;14:44. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of L-Hydroxyproline?
The CAS number of L-Hydroxyproline is 51-35-4.
What are the molecular formula and molecular weight of L-Hydroxyproline?
L-Hydroxyproline has molecular formula C5H9NO3 and molecular weight 131.130 g/mol.
What are the upstream and downstream products of L-Hydroxyproline?
For L-Hydroxyproline, Upstream Products: L-Proline, (S)-N-Boc-allylglycine, N-Boc-trans-4-hydroxy-L-proline methyl ester; Downstream Products: 1-(2-nitrophenyl)-1H-pyrrole, methyl (2S,4R)-4-[(tert-butoxycarbonyl)amino]pyrrolidine-2-carboxylate, Ethyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "L-Hydroxyproline (CAS 51-35-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1072585-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.