Losartan
Also known as: Cozaar, Lorzaar, Dup 89, Compound 89, LOS, 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, 2-Butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-methanol, (2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-imidazol-5-yl)methanol, (2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol, (2-butyl-4-chloro-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-1H-imidazol-5-yl)methanol, 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 2-n-Butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole
Losartan (CAS 114798-26-4) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H23ClN6O and a molecular weight of 422.911 g/mol. Key properties include a melting point of 183-184ºC, a boiling point of 682.0±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 366.3±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 114798-26-4
- Jingsj CID
- J-30615-5
- Molecular Formula
- C22H23ClN6O
- Molecular Weight
- 422.911 g/mol
- Category
- Organohalogen Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 183-184ºC |
|---|---|
| Boiling Point | 682.0±65.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 366.3±34.3 °C |
| Exact Mass | 422.162201 |
| PSA | 92.51000 |
| LogP | 3.57 |
| Vapor Pressure | 0.0±2.2 mmHg at 25°C |
| Refractive Index | 1.681 |
Activity & Biological Data
| Target | IC50: 20 nM (angiotensin II) |
|---|---|
| Additional Information | [1]. Burnier, M. Angiotensin II type 1 receptor blockers. Circulation, 2001. 103(6): p. 904-12. [2]. Ashry, O., et al. Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells. Respir Physiol Neurobiol, 2014. [3]. Choi, C.H., et al. Angiotensin II type I receptor and miR-155 in endometrial cancers: synergistic antiproliferative effects of anti-miR-155 and losartan on endometrial cancer cells. Gynecol Oncol, 2012. 126(1): p. 124-31. [4]. Habashi, J.P., et al. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science, 2006. 312(5770): p. 117-21. [5]. Campbell, D.J., et al. Effects of losartan on angiotensin and bradykinin peptides and angiotensin-converting enzyme. J Cardiovasc Pharmacol, 1995. 26(2): p. 233-40. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Losartan?
The CAS number of Losartan is 114798-26-4.
What are the molecular formula and molecular weight of Losartan?
Losartan has molecular formula C22H23ClN6O and molecular weight 422.911 g/mol.
What are the upstream and downstream products of Losartan?
For Losartan, Upstream Products: Trityllosartan, 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile, Losartan Carboxaldehyde; Downstream Products: 1,3-Dicyclohexylurea, Trityllosartan, Losartan potassium.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Losartan (CAS 114798-26-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30615-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.