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N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

Also known as: 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-iodoquinazoline, 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline, Lapatinib Intermediate 2, Lapatinib Impurity 25, N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine, N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodo-4-quinazolinamine, N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine, N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-iodoquinazolin-4-amine, [3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazolin-4-yl)amine

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine (CAS 231278-20-9) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C21H14ClFIN3O and a molecular weight of 505.711 g/mol. Key properties include a melting point of 222-224°C, a boiling point of 581.3±50.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 305.4±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
231278-20-9
Jingsj CID
J-29692-4
Molecular Formula
C21H14ClFIN3O
Molecular Weight
505.711 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point222-224°C
Boiling Point581.3±50.0 °C at 760 mmHg
Density1.7±0.1 g/cm3
Flash Point305.4±30.1 °C
Exact Mass504.985413
PSA47.04000
LogP6.67
Vapor Pressure0.0±1.6 mmHg at 25°C
Refractive Index1.724
Storage Conditions-20°C Freezer

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine?

The CAS number of N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine is 231278-20-9.

What are the molecular formula and molecular weight of N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine?

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine has molecular formula C21H14ClFIN3O and molecular weight 505.711 g/mol.

What are the upstream and downstream products of N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine?

For N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine, Upstream Products: 4-Chloro-6-iodoquinazoline, 3-Chloro-4-[(3-fluorobenzyl)oxy]aniline, 2-Amino-5-iodobenzonitrile; Downstream Products: Lapatinib ditosylate monohydrate, 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]quinazolin-6-yl]furan-2-carbaldehyde, Lapatinib.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine (CAS 231278-20-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-29692-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.