Atractylenolide I

Also known as: Atractylenolide-1, Atractylenolide I, ATRACTYLENOLIDE I, 8,9-Dehydroasterolide, Eudesma-4(15),7(11),8-trien-12-olide, (4aS,8aS)-3,8a-Dimethyl-5-methylene-4a,5,6,7,8,8a-hexahydronaphtho[2,3-b]furan-2(4H)-one

Atractylenolide I (CAS 73069-13-3) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C15H18O2 and a molecular weight of 230.302 g/mol. Key properties include a melting point of 121-123 °C, a boiling point of 405.0±44.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 170.8±25.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 73069-13-3
Jingsj CID: J-2437-6
Molecular Formula: C₁₅H₁₈O₂
Molecular Weight: 230.302 g/mol
Category: Esters
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	121-123 °C
Boiling Point	405.0±44.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	170.8±25.9 °C
Exact Mass	230.130676
PSA	26.30000
LogP	3.77
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.555
Storage Conditions	2-8°C
Additional Property	methanol: soluble1mg/mL, clear, colorless

Activity & Biological Data

Target	JAK2, STAT3[1], TLR4[4]
Additional Information	[1]. Atractylenolide I, et al. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I. Exp Dermatol. 2018 Feb;27(2):201-204. [2]. Gao H, et al. Anti-depressant-like effect of atractylenolide I in a mouse model of depression induced by chronic unpredictable mild stress. Exp Ther Med. 2018 Feb;15(2):1574-1579. [3]. Li W, et al. Atractylenolide I restores HO-1 expression and inhibits Ox-LDL-induced VSMCs proliferation, migration and inflammatory responses in vitro. Exp Cell Res. 2017 Apr 1;353(1):26-34. [4]. Huang JM, et al. Atractylenolide-I sensitizes human ovarian cancer cells to paclitaxel by blocking activation of TLR4/MyD88-dependent pathway. Sci Rep. 2014 Jan 23;4:3840.

Target

JAK2, STAT3[1], TLR4[4]

Additional Information

[1]. Atractylenolide I, et al. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I. Exp Dermatol. 2018 Feb;27(2):201-204. [2]. Gao H, et al. Anti-depressant-like effect of atractylenolide I in a mouse model of depression induced by chronic unpredictable mild stress. Exp Ther Med. 2018 Feb;15(2):1574-1579. [3]. Li W, et al. Atractylenolide I restores HO-1 expression and inhibits Ox-LDL-induced VSMCs proliferation, migration and inflammatory responses in vitro. Exp Cell Res. 2017 Apr 1;353(1):26-34. [4]. Huang JM, et al. Atractylenolide-I sensitizes human ovarian cancer cells to paclitaxel by blocking activation of TLR4/MyD88-dependent pathway. Sci Rep. 2014 Jan 23;4:3840.

Frequently Asked Questions

What is the CAS number of Atractylenolide I?

The CAS number of Atractylenolide I is 73069-13-3.

What are the molecular formula and molecular weight of Atractylenolide I?

Atractylenolide I has molecular formula C15H18O2 and molecular weight 230.302 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Atractylenolide I (CAS 73069-13-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2437-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.