Dehydrocostus lactone

Also known as: Dehydrocostunolide, (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one, Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-, Costus lactone, dehydro-, MFCD00210277

Dehydrocostus lactone (CAS 477-43-0) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C15H18O2 and a molecular weight of 230.302 g/mol. Key properties include a melting point of 59 °C, a boiling point of 383.7±42.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 161.2±25.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 477-43-0
Jingsj CID: J-18833-3
Molecular Formula: C₁₅H₁₈O₂
Molecular Weight: 230.302 g/mol
Category: Esters
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	59 °C
Boiling Point	383.7±42.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	161.2±25.3 °C
Exact Mass	230.130676
PSA	26.30000
LogP	3.40
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.536

Activity & Biological Data

Additional Information	[1]. Eun Ji Kim, et al. Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa. Food and Chemical Toxicology Volume 46, Issue 12, December 2008, Pages 3651–3658 [2]. Oh GS, et al. Dehydrocostus lactone enhances tumor necrosis factor-alpha-induced apoptosis of human leukemia HL-60 cells. Immunopharmacol Immunotoxicol. 2004 May;26(2):163-75. [3]. Lee HJ, et al. A sesquiterpene, dehydrocostus lactone, inhibits the expression of inducible nitric oxide synthase and TNF-alpha in LPS-activated macrophages. Planta Med. 1999 Mar;65(2):104-8. [4]. Taniguchi M, et al. COSTUNOLIDE AND DEHYDROCOSTUS LACTONE AS INHIBITORS OF KILLING FUNCTION OF CYTOTOXIC T LYMPHOCYTES. Bioscience, Biotechnology, and Biochemistry, 1995, 59 (11): 2064-2067

Additional Information

[1]. Eun Ji Kim, et al. Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa. Food and Chemical Toxicology Volume 46, Issue 12, December 2008, Pages 3651–3658 [2]. Oh GS, et al. Dehydrocostus lactone enhances tumor necrosis factor-alpha-induced apoptosis of human leukemia HL-60 cells. Immunopharmacol Immunotoxicol. 2004 May;26(2):163-75. [3]. Lee HJ, et al. A sesquiterpene, dehydrocostus lactone, inhibits the expression of inducible nitric oxide synthase and TNF-alpha in LPS-activated macrophages. Planta Med. 1999 Mar;65(2):104-8. [4]. Taniguchi M, et al. COSTUNOLIDE AND DEHYDROCOSTUS LACTONE AS INHIBITORS OF KILLING FUNCTION OF CYTOTOXIC T LYMPHOCYTES. Bioscience, Biotechnology, and Biochemistry, 1995, 59 (11): 2064-2067

Customs & Trade Information

HS Code	29089000

Frequently Asked Questions

What is the CAS number of Dehydrocostus lactone?

The CAS number of Dehydrocostus lactone is 477-43-0.

What are the molecular formula and molecular weight of Dehydrocostus lactone?

Dehydrocostus lactone has molecular formula C15H18O2 and molecular weight 230.302 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Dehydrocostus lactone (CAS 477-43-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18833-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.