trans-4-Hydroxy-D-proline methyl ester hydrochloride

Also known as: (2R,4S)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride, (4S)-4-Hydroxy-D-proline methyl ester hydrochloride, (S)-4-Hydroxy-D-proline methyl ester hydrochloride, Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride, D-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4S)-, H-D-trans-Hyp-OMe.HCl

trans-4-Hydroxy-D-proline methyl ester hydrochloride (CAS 481704-21-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C6H12ClNO3 and a molecular weight of 181.617 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 481704-21-6
Jingsj CID: J-1987425-0
Molecular Formula: C₆H₁₂ClNO₃
Molecular Weight: 181.617 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	181.050568
PSA	58.56000
LogP	0.01300

Activity & Biological Data

Target	Non-cleavable
Additional Information	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Frequently Asked Questions

What is the CAS number of trans-4-Hydroxy-D-proline methyl ester hydrochloride?

The CAS number of trans-4-Hydroxy-D-proline methyl ester hydrochloride is 481704-21-6.

What are the molecular formula and molecular weight of trans-4-Hydroxy-D-proline methyl ester hydrochloride?

trans-4-Hydroxy-D-proline methyl ester hydrochloride has molecular formula C6H12ClNO3 and molecular weight 181.617 g/mol.

What are the upstream and downstream products of trans-4-Hydroxy-D-proline methyl ester hydrochloride?

For trans-4-Hydroxy-D-proline methyl ester hydrochloride, Upstream Products: trans-4-Hydroxy-D-proline, Methanol, trans-4-Hydroxy-D-proline hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "trans-4-Hydroxy-D-proline methyl ester hydrochloride (CAS 481704-21-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987425-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.