Bendamustine

Also known as: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid, 4-[5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid, 4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoic acid, Bendamustina, Bendamustinum, SDX 105, Treanda, UNII-9266D3PQPQ

Bendamustine (CAS 16506-27-7) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C16H21Cl2N3O2 and a molecular weight of 358.263 g/mol. Key properties include a boiling point of 585.2±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 307.7±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 16506-27-7
Jingsj CID: J-1980154-8
Molecular Formula: C₁₆H₂₁Cl₂N₃O₂
Molecular Weight: 358.263 g/mol
Category: Aromatic Hydrocarbons
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	585.2±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	307.7±30.1 °C
Exact Mass	357.101074
PSA	58.36000
LogP	2.69
Vapor Pressure	0.0±1.7 mmHg at 25°C
Refractive Index	1.599

Activity & Biological Data

Target	DNA Alkylator/Crosslinker[1]
Additional Information	[1]. Leoni LM, et al. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 2008 Jan 1;14(1):309-17. [2]. Cives M, et al. Bendamustine overcomes resistance to melphalan in myeloma cell lines by inducing cell death through mitotic catastrophe. Cell Signal. 2013 May;25(5):1108-17. [3]. Ackler S, et al. Navitoclax (ABT-263) and bendamustine ± rituximab induce enhanced killing of non-Hodgkin's lymphoma tumours in vivo. Br J Pharmacol. 2012 Oct;167(4):881-91.

Target

DNA Alkylator/Crosslinker[1]

Additional Information

[1]. Leoni LM, et al. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 2008 Jan 1;14(1):309-17. [2]. Cives M, et al. Bendamustine overcomes resistance to melphalan in myeloma cell lines by inducing cell death through mitotic catastrophe. Cell Signal. 2013 May;25(5):1108-17. [3]. Ackler S, et al. Navitoclax (ABT-263) and bendamustine ± rituximab induce enhanced killing of non-Hodgkin's lymphoma tumours in vivo. Br J Pharmacol. 2012 Oct;167(4):881-91.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Bendamustine?

The CAS number of Bendamustine is 16506-27-7.

What are the molecular formula and molecular weight of Bendamustine?

Bendamustine has molecular formula C16H21Cl2N3O2 and molecular weight 358.263 g/mol.

What are the upstream and downstream products of Bendamustine?

For Bendamustine, Upstream Products: 5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester, Bendamustine hydrochloride, Ethyl 4-(5-amino-1-methyl-1H-benzimidazol-2-yl)butanoate; Downstream Products: Methyl 5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Bendamustine (CAS 16506-27-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1980154-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.