Naproxcinod

Also known as: AZD 3582, AZD-3582, HCT 3012, HCT-3012, Nitronaproxen, 4-(NITROOXY)BUTYL (2S)-2-(6-METHOXY-2-NAPHTHYL)PROPANOATE, AKFJWRDCWYYTIG-ZDUSSCGKSA-N, naproxen-n-butyl nitrate

Naproxcinod (CAS 163133-43-5) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C18H21NO6 and a molecular weight of 347.36200 g/mol. Key properties include a boiling point of 489.475ºC at 760 mmHg, a density of 1.213 and a flash point of 193.208ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 163133-43-5
Jingsj CID: J-1974993-2
Molecular Formula: C₁₈H₂₁NO₆
Molecular Weight: 347.36200 g/mol
Category: Aromatic Hydrocarbons
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	489.475ºC at 760 mmHg
Density	1.213
Flash Point	193.208ºC
Exact Mass	347.13700
PSA	90.58000
LogP	4.00680

Activity & Biological Data

Additional Information	[1]. Berndt G, et al. A common pathway of nitric oxide release from AZD3582 and glyceryl trinitrate. Eur J Pharm Sci. 2004 Feb;21(2-3):331-5. [2]. Berndt G, et al. AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells. Eur J Pharm Sci. 2005 Jun;25(2-3):229-35. [3]. Uaesoontrachoon K, et al. Long-term treatment with naproxcinod significantly improves skeletal and cardiac disease phenotype in the mdx mouse model of dystrophy. Hum Mol Genet. 2014 Jun 15;23(12):3239-49.

Additional Information

[1]. Berndt G, et al. A common pathway of nitric oxide release from AZD3582 and glyceryl trinitrate. Eur J Pharm Sci. 2004 Feb;21(2-3):331-5. [2]. Berndt G, et al. AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells. Eur J Pharm Sci. 2005 Jun;25(2-3):229-35. [3]. Uaesoontrachoon K, et al. Long-term treatment with naproxcinod significantly improves skeletal and cardiac disease phenotype in the mdx mouse model of dystrophy. Hum Mol Genet. 2014 Jun 15;23(12):3239-49.

Frequently Asked Questions

What is the CAS number of Naproxcinod?

The CAS number of Naproxcinod is 163133-43-5.

What are the molecular formula and molecular weight of Naproxcinod?

Naproxcinod has molecular formula C18H21NO6 and molecular weight 347.36200 g/mol.

What are the upstream and downstream products of Naproxcinod?

For Naproxcinod, Upstream Products: Naproxen, 4-bromobutyl nitrate, (S)-(+)-Naproxen chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Naproxcinod (CAS 163133-43-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974993-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.