Naproxen
Also known as: (+)-Naproxen, (S)-Naproxen, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, (S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, Naprosyn, Aleve, Anaprox, APRONAX, NAPROSYNE, Naproxeno, Naproxenum, Equiproxen, Piproxen, NAPROXENE, (2S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid, MFCD00010500, EINECS 244-838-7
Naproxen (CAS 22204-53-1) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C14H14O3 and a molecular weight of 230.259 g/mol. Key properties include a melting point of 152-154 °C(lit.), a boiling point of 403.9±20.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 154.5±15.3 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. It is listed by 1 supplier, from 18.32 to 45.00 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 22204-53-1
- Jingsj CID
- J-18619-5
- Molecular Formula
- C14H14O3
- Molecular Weight
- 230.259 g/mol
- Category
- Aromatic Hydrocarbons
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | >99.0%(GC)(T) 500g | ¥9,162.00 | $2.74 /gBest ¥18.32/g CNY | CN China MOQ 500g | |
In Stock | >99.0%(GC)(T) 25g | ¥1,125.00 | $6.73 /g ¥45.00/g CNY | CN China MOQ 25g |
Physicochemical Properties
| Melting Point | 152-154 °C(lit.) |
|---|---|
| Boiling Point | 403.9±20.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 154.5±15.3 °C |
| Exact Mass | 230.094299 |
| PSA | 46.53000 |
| LogP | 3.00 |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| Refractive Index | 1.609 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
Activity & Biological Data
| Target | COX-2:5.65 μM (IC50) COX-1:9.55 μM (IC50) |
|---|---|
| Additional Information | [1]. Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7. [2]. Rosa AC, et al. Prevention of bleomycin-induced lung inflammation and fibrosis in mice by naproxen and JNJ7777120 treatment. J Pharmacol Exp Ther. 2014 Nov;351(2):308-16. [3]. Krekels EH, et al. Pharmacokinetic-pharmacodynamic modeling of the inhibitory effects of naproxen on the time-courses of inflammatory pain, fever, and the ex vivo synthesis of TXB2 and PGE2 in rats. |
Customs & Trade Information
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Naproxen?
The CAS number of Naproxen is 22204-53-1.
What are the molecular formula and molecular weight of Naproxen?
Naproxen has molecular formula C14H14O3 and molecular weight 230.259 g/mol.
Which suppliers offer Naproxen?
1 supplier(s) listed; reference unit price ¥18.32–45.00 /g.
Is Naproxen hazardous?
Naproxen has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.
What are the upstream and downstream products of Naproxen?
For Naproxen, Upstream Products: (±)-2-(6-Methoxy-2-naphthyl)propionic acid, 6-Methoxy-2-naphthaleneacetic acid; Downstream Products: (S)-(+)-Naproxen chloride, 2-Acetyl-6-methoxynaphthalene, O-Desmethylnaproxen.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Naproxen (CAS 22204-53-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18619-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.