Agomelatine
Also known as: N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide, N-[2-(7-Methoxynaphthalen-1-yl)ethyl]acetamide, N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide, Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-, Valdoxan, Melitor, Thymanax, S 20098, S20098, CS-1963, Unii-137R1N49ad
Agomelatine (CAS 138112-76-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H17NO2 and a molecular weight of 243.301 g/mol. Key properties include a melting point of 107-109ºC, a boiling point of 478.8±28.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 243.4±24.0 °C. It is classified under GHS with signal word Warning and hazard statements H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 138112-76-2
- Jingsj CID
- J-1963081-0
- Molecular Formula
- C15H17NO2
- Molecular Weight
- 243.301 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 107-109ºC |
|---|---|
| Boiling Point | 478.8±28.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 243.4±24.0 °C |
| Exact Mass | 243.125931 |
| PSA | 38.33000 |
| LogP | 2.27 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.582 |
| Storage Conditions | -20°C Freezer |
GHS Safety & Compliance
- H400 — Very toxic to aquatic life
Activity & Biological Data
| Additional Information | [1]. Pan L, Kardono LB, Riswan S, Chai H, Carcache de Blanco EJ, Pannell CM, Soejarto DD, McCloud TG, Newman DJ, Kinghorn AD.Isolation and characterization of minor analogues of silvestrol and other constituents from a large-scale re-collection of Aglaia foveolata.J Nat Prod. 2010 Nov 29;73(11):1873-8. [2]. Zajecka J, Schatzberg A, Stahl S. et al. Efficacy and safety of agomelatine in the treatment of major depressive disorder: a multicenter, randomized, double-blind, placebo-controlled trial. J Clin Psychopharmacol. 2010 Apr;30(2):135-44. [3]. Randy A Sansone, Lori A Sansone. Agomelatine A Novel Antidepressant. Innov Clin Neurosci. 2011 November; 8(11): 10-14. [4]. Michele Fornaro, Davide Prestia, Salvatore Colicchio, and Giulio Perugi. A Systematic, Updated Review on the Antidepressant Agomelatine Focusing on its Melatonergic Modulation. Curr Neuropharmacol. 2010 September; 8(3): 287-304. [5]. Agomelatine |
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Customs & Trade Information
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Agomelatine?
The CAS number of Agomelatine is 138112-76-2.
What are the molecular formula and molecular weight of Agomelatine?
Agomelatine has molecular formula C15H17NO2 and molecular weight 243.301 g/mol.
Is Agomelatine hazardous?
Agomelatine has GHS signal word Warning and hazard statements H400 — Very toxic to aquatic life.
What are the upstream and downstream products of Agomelatine?
For Agomelatine, Upstream Products: 7-Methoxy-1-naphthylacetonitrile, 2-(7-Methoxynaphthalen-1-yl)ethanamine, 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride; Downstream Products: 7-Desmethylagomelatine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Agomelatine (CAS 138112-76-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963081-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.