7-Desmethylagomelatine

Also known as: N-(2-(7-Hydroxynaphthalen-1-yl)ethyl)acetamide, N-[2-(7-Hydroxy-1-naphthyl)ethyl]acetamide, Acetamide, N-[2-(7-hydroxy-1-naphthalenyl)ethyl]-, O-Demethylagomelatine, 7-Demethylagomelatine, Desmethyl agomelatine, Agomelatine Impurity 3, Agomelatine Impurity 7, Agomelatine Impurity 10, Agomelatine Impurity 12, Agomelatine Impurity 14 Hydrochloride

7-Desmethylagomelatine (CAS 152302-45-9) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C14H15NO2 and a molecular weight of 229.274 g/mol. Key properties include a boiling point of 511.3±33.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 263.0±25.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 152302-45-9
Jingsj CID: J-1970057-3
Molecular Formula: C₁₄H₁₅NO₂
Molecular Weight: 229.274 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	511.3±33.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	263.0±25.4 °C
Exact Mass	229.110275
PSA	52.82000
LogP	1.62
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.624

Activity & Biological Data

Additional Information	[1]. Millan MJ, et al. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J Pharmacol Exp Ther. 2003 Sep;306(3):954-64. [2]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:60-6.

Additional Information

[1]. Millan MJ, et al. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J Pharmacol Exp Ther. 2003 Sep;306(3):954-64. [2]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:60-6.

Customs & Trade Information

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 7-Desmethylagomelatine?

The CAS number of 7-Desmethylagomelatine is 152302-45-9.

What are the molecular formula and molecular weight of 7-Desmethylagomelatine?

7-Desmethylagomelatine has molecular formula C14H15NO2 and molecular weight 229.274 g/mol.

What are the upstream and downstream products of 7-Desmethylagomelatine?

For 7-Desmethylagomelatine, Upstream Products: Agomelatine, 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride, 7-Hydroxy-3,4-dihydronaphthalen-1(2H)-one; Downstream Products: Agomelatine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "7-Desmethylagomelatine (CAS 152302-45-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970057-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.