Desloratadine

Also known as: 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Aerius, Allex, AzoMyr, Clarinex, Neoclarityn, Opulis, Sch34117, UNII-FVF865388R, descarboethoxyloratadine, Loratadine Related Compound A

Desloratadine (CAS 100643-71-8) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H19ClN2 and a molecular weight of 310.821 g/mol. Key properties include a melting point of 150-151°C, a boiling point of 467.9±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 236.8±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 100643-71-8
Jingsj CID: J-18950-3
Molecular Formula: C₁₉H₁₉ClN₂
Molecular Weight: 310.821 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	150-151°C
Boiling Point	467.9±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	236.8±28.7 °C
Exact Mass	310.123688
PSA	24.92000
LogP	6.77
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.626

Activity & Biological Data

Additional Information	[1]. Geha, R.S. and E.O. Meltzer, Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001. 107(4): p. 751-62. [2]. Schroeder, J.T., et al., Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001. 31(9): p. 1369-77. [3]. Anthes, J.C., et al., Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. Eur J Pharmacol, 2002. 449(3): p. 229-37.

Additional Information

[1]. Geha, R.S. and E.O. Meltzer, Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001. 107(4): p. 751-62. [2]. Schroeder, J.T., et al., Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001. 31(9): p. 1369-77. [3]. Anthes, J.C., et al., Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. Eur J Pharmacol, 2002. 449(3): p. 229-37.

Frequently Asked Questions

What is the CAS number of Desloratadine?

The CAS number of Desloratadine is 100643-71-8.

What are the molecular formula and molecular weight of Desloratadine?

Desloratadine has molecular formula C19H19ClN2 and molecular weight 310.821 g/mol.

What are the upstream and downstream products of Desloratadine?

For Desloratadine, Upstream Products: Loratadine, 8-Chloro-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, N-tert-butyl-3-methylpyridine-2-carboxamide; Downstream Products: Rupatadine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Desloratadine (CAS 100643-71-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18950-3 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.