Trifluridine
Also known as: Trifluorothymidine, Viroptic, α,α,α-Trifluorothymidine, 2'-Deoxy-5-(trifluoromethyl)uridine, 5-Trifluoromethyl-2'-deoxyuridine, 5-Trifluoro-2'-deoxythymidine, TFT, FTD, VIROPTIC, Virophta, 1-(2-Deoxy-β-D-glycero-pentofuranosyl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-ribofuranosyl)-5-(trifluoromethyl)-, 2'-Deoxy-5-trifluoromethyluridine, Uridine, 2'-deoxy-5-(trifluoromethyl)-
Trifluridine (CAS 70-00-8) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H11F3N2O5 and a molecular weight of 296.200 g/mol. Key properties include a melting point of 190-193 °C(lit.) and a density of 1.6±0.1 g/cm3. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. It is listed by 1 supplier, from 9.90 to 6,912.00 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 70-00-8
- Jingsj CID
- J-1991416-1
- Molecular Formula
- C10H11F3N2O5
- Molecular Weight
- 296.200 g/mol
- Category
- Organohalogen Compounds
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | >97.0%(LC)(T) 100mg | ¥990.00 | $1.48 /mgBest ¥9.90/mg CNY | CN China MOQ 100mg | |
In Stock | >97.0%(LC)(T) 1g | ¥6,912.00 | $1,034.34 /g ¥6,912.00/g CNY | CN China MOQ 1g |
Physicochemical Properties
| Melting Point | 190-193 °C(lit.) |
|---|---|
| Density | 1.6±0.1 g/cm3 |
| Exact Mass | 296.062012 |
| PSA | 104.55000 |
| LogP | 0.07 |
| Refractive Index | 1.534 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
- H332 — Harmful if inhaled
- H351 — Suspected of causing cancer
Activity & Biological Data
| Additional Information | [1]. Suzuki N, et al. Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes. Int J Oncol. 2011 Jul;39(1):263-70. [2]. Suzuki N, et al. Trifluorothymidine exhibits potent antitumor activity via the induction of DNA double-strand breaks. Exp Ther Med. 2011 May;2(3):393-397. [3]. Temmink OH, et al. Irinotecan-induced cytotoxicity to colon cancer cells in vitro is stimulated by pre-incubation withtrifluorothymidine. Eur J Cancer. 2007 Jan;43(1):175-83. [4]. Okayama T, et al. Involvement of concentrative nucleoside transporter 1 in intestinal absorption of trifluorothymidine, a novel antitumor nucleoside, in rats. J Pharmacol Exp Ther. 2012 Feb;340(2):457-62. |
|---|
Frequently Asked Questions
What is the CAS number of Trifluridine?
The CAS number of Trifluridine is 70-00-8.
What are the molecular formula and molecular weight of Trifluridine?
Trifluridine has molecular formula C10H11F3N2O5 and molecular weight 296.200 g/mol.
Which suppliers offer Trifluridine?
1 supplier(s) listed; reference unit price ¥9.90–6912.00 /mg.
Is Trifluridine hazardous?
Trifluridine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.
What are the upstream and downstream products of Trifluridine?
For Trifluridine, Upstream Products: Trifluoromethyl iodide, 2'-deoxyuridine, 1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one; Downstream Products: 5-Carboxy-2'-deoxyuridine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Trifluridine (CAS 70-00-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1991416-1 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.