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2-Hydroxy-5-(trifluoromethyl)pyridine

Also known as: 5-(Trifluoromethyl)-2(1H)-pyridone, 5-(Trifluoromethyl)-2-pyridinol, 5-(Trifluoromethyl)pyridin-2-ol, 5-Trifluoromethyl-2(1H)-pyridinone, 5-Trifluoromethyl-2-hydroxypyridine, 5-(Trifluoromethyl)pyridin-2(1H)-one, 5-Trifluoromethyl-pyridin-2-ol

2-Hydroxy-5-(trifluoromethyl)pyridine (CAS 33252-63-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H4F3NO and a molecular weight of 163.097 g/mol. Key properties include a melting point of 145-149 °C(lit.), a boiling point of 286.8±35.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 127.3±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
33252-63-0
Jingsj CID
J-1314152-1
Molecular Formula
C6H4F3NO
Molecular Weight
163.097 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point145-149 °C(lit.)
Boiling Point286.8±35.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point127.3±25.9 °C
Exact Mass163.024506
PSA33.12000
LogP1.10
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.457

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Hydroxy-5-(trifluoromethyl)pyridine?

The CAS number of 2-Hydroxy-5-(trifluoromethyl)pyridine is 33252-63-0.

What are the molecular formula and molecular weight of 2-Hydroxy-5-(trifluoromethyl)pyridine?

2-Hydroxy-5-(trifluoromethyl)pyridine has molecular formula C6H4F3NO and molecular weight 163.097 g/mol.

Is 2-Hydroxy-5-(trifluoromethyl)pyridine hazardous?

2-Hydroxy-5-(trifluoromethyl)pyridine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 2-Hydroxy-5-(trifluoromethyl)pyridine?

For 2-Hydroxy-5-(trifluoromethyl)pyridine, Upstream Products: 2-Chloro-5-(trifluoromethyl)pyridine, 2-Chloro-5-(trichloromethyl)pyridine; Downstream Products: 2-Hydroxy-3-nitro-5-(trifluoromethyl)pyridine, 2-methyl-2-[(5-trifluoromethylpyridin-2-yl)oxy]propionic acid, 2-HYDRAZINO-3-NITRO-5-(TRIFLUOROMETHYL)PYRIDINE.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Hydroxy-5-(trifluoromethyl)pyridine (CAS 33252-63-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1314152-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.