Taranabant

Also known as: MK-0364, MK 0364, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[(5-(trifluoromethyl)pyridin-2-yl)oxy]propanamide, Propanamide, N-((1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)-2-pyridinyl)oxy)-, N-(3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide, Taranabant [usan], UNII-X9U622S114

Taranabant (CAS 701977-09-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C27H25ClF3N3O2 and a molecular weight of 515.95500 g/mol. Key properties include a boiling point of 634.2ºC at 760 mmHg and a density of 1.3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 701977-09-5
Jingsj CID: J-1126289-8
Molecular Formula: C₂₇H₂₅ClF₃N₃O₂
Molecular Weight: 515.95500 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	634.2ºC at 760 mmHg
Density	1.3
Exact Mass	515.15900
PSA	75.01000
LogP	6.70498
Storage Conditions	2-8℃

Activity & Biological Data

Target	IC50: 0.3 nM (hCB1R), 0.4 nM (rCB1R)[1] Ki: 0.13 nM (hCB1R), 0.27 nM (rCB1R)[1]
Additional Information	[1]. Fong TM, et al. Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents. J Pharmacol Exp T [2]. Lin LS, et al. Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity. J M

Target

IC50: 0.3 nM (hCB1R), 0.4 nM (rCB1R)[1] Ki: 0.13 nM (hCB1R), 0.27 nM (rCB1R)[1]

Additional Information

[1]. Fong TM, et al. Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents. J Pharmacol Exp T [2]. Lin LS, et al. Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity. J M

Frequently Asked Questions

What is the CAS number of Taranabant?

The CAS number of Taranabant is 701977-09-5.

What are the molecular formula and molecular weight of Taranabant?

Taranabant has molecular formula C27H25ClF3N3O2 and molecular weight 515.95500 g/mol.

What are the upstream and downstream products of Taranabant?

For Taranabant, Upstream Products: 3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-one, 4-Chlorobenzyl bromide, Methyl 2-(3-bromophenyl)acetate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Taranabant (CAS 701977-09-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1126289-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.