2-Chloro-5-(trifluoromethyl)pyridine
Also known as: 2-chloro-5-(trifluoromethyl)pyridine, 2-Chloro-5-trifluoromethylpyridine, 2,5-CTF, 5-CTF, EINECS 257-856-5, MFCD00042225
2-Chloro-5-(trifluoromethyl)pyridine (CAS 52334-81-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H3ClF3N and a molecular weight of 181.543 g/mol. Key properties include a melting point of 32-34 °C(lit.), a boiling point of 171.6±35.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 57.6±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 52334-81-3
- Jingsj CID
- J-1135709-8
- Molecular Formula
- C6H3ClF3N
- Molecular Weight
- 181.543 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 32-34 °C(lit.) |
|---|---|
| Boiling Point | 171.6±35.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 57.6±25.9 °C |
| Exact Mass | 180.990616 |
| PSA | 12.89000 |
| LogP | 2.44 |
| Vapor Pressure | 1.8±0.3 mmHg at 25°C |
| Refractive Index | 1.447 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Customs & Trade Information
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 2-Chloro-5-(trifluoromethyl)pyridine?
The CAS number of 2-Chloro-5-(trifluoromethyl)pyridine is 52334-81-3.
What are the molecular formula and molecular weight of 2-Chloro-5-(trifluoromethyl)pyridine?
2-Chloro-5-(trifluoromethyl)pyridine has molecular formula C6H3ClF3N and molecular weight 181.543 g/mol.
Is 2-Chloro-5-(trifluoromethyl)pyridine hazardous?
2-Chloro-5-(trifluoromethyl)pyridine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 2-Chloro-5-(trifluoromethyl)pyridine?
For 2-Chloro-5-(trifluoromethyl)pyridine, Upstream Products: 3-(Trifluoromethyl)pyridine 1-oxide, 2-Hydroxy-5-(trifluoromethyl)pyridine, 2-Chloro-5-(trichloromethyl)pyridine; Downstream Products: 2-Hydroxy-5-(trifluoromethyl)pyridine, 2-methyl-2-[(5-trifluoromethylpyridin-2-yl)oxy]propionic acid, 1-[5-(Trifluoromethyl)pyridin-2-yl]-1,4-diazepane.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Chloro-5-(trifluoromethyl)pyridine (CAS 52334-81-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1135709-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.