Troglitazone

Also known as: CS-045, Rezulin, Romglizone, Prelay, Romozin, Noscal, GR 92132X, CI 991, 5-[[4-[(6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, 5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione, MFCD00878416

Troglitazone (CAS 97322-87-7) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C24H27NO5S and a molecular weight of 441.540 g/mol. Key properties include a melting point of 184-186°C, a boiling point of 657.0±55.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 351.2±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 97322-87-7
Jingsj CID: J-30342-2
Molecular Formula: C₂₄H₂₇NO₅S
Molecular Weight: 441.540 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	184-186°C
Boiling Point	657.0±55.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	351.2±31.5 °C
Exact Mass	441.160980
PSA	110.16000
LogP	4.99
Vapor Pressure	0.0±2.1 mmHg at 25°C
Refractive Index	1.608
Additional Property	DMSO: 20 mg/mL

Activity & Biological Data

Target	PPARγ:550 nM (EC50, Human PPARγ)
Additional Information	[1]. Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50. [2]. Fujita M, et al. In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer. J Exp Clin Cancer Res. 2017 Jul 3;36(1):91. [3]. Nazim UM, et al. PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux. Oncotarget. 2017 Apr 18;8(16):26819-26831.

Target

PPARγ:550 nM (EC50, Human PPARγ)

Additional Information

[1]. Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50. [2]. Fujita M, et al. In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer. J Exp Clin Cancer Res. 2017 Jul 3;36(1):91. [3]. Nazim UM, et al. PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux. Oncotarget. 2017 Apr 18;8(16):26819-26831.

Frequently Asked Questions

What is the CAS number of Troglitazone?

The CAS number of Troglitazone is 97322-87-7.

What are the molecular formula and molecular weight of Troglitazone?

Troglitazone has molecular formula C24H27NO5S and molecular weight 441.540 g/mol.

What are the upstream and downstream products of Troglitazone?

For Troglitazone, Upstream Products: 2-Methoxyethanol, 2-(Hydroxymethyl)-2,5,7,8-tetramethyl-6-chromanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Troglitazone (CAS 97322-87-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30342-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.