Bafilomycin A1

巴佛洛霉素A1

Also known as: Baf-A1, Bafilomycin A1 from Streptomyces griseus, bafilomycin, bafilomycin A, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one, (5R)-2,4-Dideoxy-1-C-{(2S,3R,4S)-3-hydroxy-4-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-2-pentanyl}-5-isopropyl-4-methyl-α-D-threo-pentopyranose

Bafilomycin A1 (CAS 88899-55-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C35H58O9 and a molecular weight of 622.830 g/mol. It is also known as Baf-A1, Bafilomycin A1 from Streptomyces griseus and bafilomycin. Key properties include a boiling point of 770.1±60.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 232.2±26.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 88899-55-2
Jingsj CID: J-9086-3
Molecular Formula: C₃₅H₅₈O₉
Chinese Name: 巴佛洛霉素A1
Molecular Weight: 622.830 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	770.1±60.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	232.2±26.4 °C
Exact Mass	622.408081
PSA	134.91000
LogP	3.88
Vapor Pressure	0.0±6.0 mmHg at 25°C
Refractive Index	1.535

Activity & Biological Data

Target	H+ ATPase[1]
Additional Information	[1]. Yuan N, et al. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica. 2015 Mar;100(3):345-56. [2]. Lu X, et al. Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expression. Exp Ther Med. 2015 Nov;10(5):1829-1834. [3]. Ohkuma S, et al. Inhibition of cell growth by bafilomycin A1, a selective inhibitor of vacuolar H(+)-ATPase. In Vitro Cell Dev Biol Anim. 1993 Nov;29A(11):862-6. [4]. Ohta T, et al. Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-1. J Pathol. 1998 Jul;185(3):324-30.

Target

H+ ATPase[1]

Additional Information

[1]. Yuan N, et al. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica. 2015 Mar;100(3):345-56. [2]. Lu X, et al. Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expression. Exp Ther Med. 2015 Nov;10(5):1829-1834. [3]. Ohkuma S, et al. Inhibition of cell growth by bafilomycin A1, a selective inhibitor of vacuolar H(+)-ATPase. In Vitro Cell Dev Biol Anim. 1993 Nov;29A(11):862-6. [4]. Ohta T, et al. Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-1. J Pathol. 1998 Jul;185(3):324-30.

Frequently Asked Questions

What is the CAS number of Bafilomycin A1?

The CAS number of Bafilomycin A1 is 88899-55-2.

What are the molecular formula and molecular weight of Bafilomycin A1?

Bafilomycin A1 has molecular formula C35H58O9 and molecular weight 622.830 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Bafilomycin A1 (CAS 88899-55-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-9086-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.