Itraconazole
伊曲康唑
Also known as: Sporanox, Oriconazole, R51211, Canditral, Triasporin, Itrizole, Orungal, Sempera, Candistat, Cladosal 100, Itrac, Sporanos
Itraconazole (CAS 84625-61-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C35H38Cl2N8O4 and a molecular weight of 705.633 g/mol. It is also known as Sporanox, Oriconazole and R51211. Key properties include a melting point of 166°C, a boiling point of 850.0±75.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 467.9±37.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 84625-61-6
- Jingsj CID
- J-37943-6
- Molecular Formula
- C35H38Cl2N8O4
- Chinese Name
- 伊曲康唑
- Molecular Weight
- 705.633 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 166°C |
|---|---|
| Boiling Point | 850.0±75.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 467.9±37.1 °C |
| Exact Mass | 704.239319 |
| PSA | 104.70000 |
| LogP | 4.35 |
| Vapor Pressure | 0.0±3.2 mmHg at 25°C |
| Refractive Index | 1.678 |
| Storage Conditions | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Additional Property | chloroform: 50 mg/mL, clear, colorless |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Kim, J., et al., Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell, 2010. 17(4): p. 388-99. [2]. Chong, C.R., et al., Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol, 2007. 2(4): p. 263-70. [3]. Shi, W., et al., Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling. J Med Chem, 2011. 54(20): p. 7363-74. [4]. Olkkola, K.T., J.T. Backman, and P.J. Neuvonen, Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clinical Pharmacology & Therapeutics, 1994. 55(5): p. 481-485. |
|---|
Customs & Trade Information
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Itraconazole?
The CAS number of Itraconazole is 84625-61-6.
What are the molecular formula and molecular weight of Itraconazole?
Itraconazole has molecular formula C35H38Cl2N8O4 and molecular weight 705.633 g/mol.
Is Itraconazole hazardous?
Itraconazole has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Itraconazole?
For Itraconazole, Upstream Products: 2-Bromobutane.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Itraconazole (CAS 84625-61-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37943-6 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.