Rotenone

Also known as: (2R,6aS,12aS)-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, Tubatoxin, Derris root extract, (-)-Rotenone, Noxfire, Paraderil, Protax

Rotenone (CAS 83-79-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C23H22O6 and a molecular weight of 394.417 g/mol. Key properties include a melting point of 159-164 °C(lit.), a boiling point of 559.8±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 244.6±30.2 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 83-79-4
Jingsj CID: J-31071-2
Molecular Formula: C₂₃H₂₂O₆
Molecular Weight: 394.417 g/mol
Category: Ketones
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	159-164 °C(lit.)
Boiling Point	559.8±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	244.6±30.2 °C
Exact Mass	394.141632
PSA	63.22000
LogP	4.65
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.591

GHS Safety & Compliance

Acute Toxicity / Environmental HazardSignal word: Danger

H301 — Toxic if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation
H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

Additional Information	[1]. Khadrawy YA, et al. Cerebellar neurochemical and histopathological changes in rat model of Parkinson's disease induced by intrastriatal injection of rotenone. Gen Physiol Biophys. 2016 Nov 30 [2]. Guan Q, et al. RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways. Neurochem Res. 2016 Nov 30 [3]. Kishore Kumar SN, et al. Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis. Redox Rep. 2016 Nov 24:1-12 [4]. Zhang ZN, et al. Subcutaneous rotenone rat model of Parkinson's disease: dose exploration study. Brain Res. 2016 Nov 19. pii: S0006-8993(16)30776-4

Additional Information

[1]. Khadrawy YA, et al. Cerebellar neurochemical and histopathological changes in rat model of Parkinson's disease induced by intrastriatal injection of rotenone. Gen Physiol Biophys. 2016 Nov 30 [2]. Guan Q, et al. RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways. Neurochem Res. 2016 Nov 30 [3]. Kishore Kumar SN, et al. Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis. Redox Rep. 2016 Nov 24:1-12 [4]. Zhang ZN, et al. Subcutaneous rotenone rat model of Parkinson's disease: dose exploration study. Brain Res. 2016 Nov 19. pii: S0006-8993(16)30776-4

Frequently Asked Questions

What is the CAS number of Rotenone?

The CAS number of Rotenone is 83-79-4.

What are the molecular formula and molecular weight of Rotenone?

Rotenone has molecular formula C23H22O6 and molecular weight 394.417 g/mol.

Is Rotenone hazardous?

Rotenone has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Rotenone?

For Rotenone, Upstream Products: Diazomethane; Downstream Products: Deguelin, Dehydrodeguelin, Dihydrorotenone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Rotenone (CAS 83-79-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-31071-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.