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4,4'-Diaminodiphenylsulfone

Also known as: Dapsone, Bis(p-aminophenyl)sulfone, 4,4'-Sulfonyldianiline, Benzenamine, 4,4'-sulfonylbis-, 4-(4-aminophenyl)sulfonylaniline, 4-Aminophenylsulfone, ACZONE, Aradur 976-1, Diaphenylsulfone, Seikacure S

4,4'-Diaminodiphenylsulfone (CAS 80-08-0) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C12H12N2O2S and a molecular weight of 248.301 g/mol. Key properties include a melting point of 175-177 °C(lit.), a boiling point of 511.7±35.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 263.2±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
80-08-0
Jingsj CID
J-47595-0
Molecular Formula
C12H12N2O2S
Molecular Weight
248.301 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Melting Point175-177 °C(lit.)
Boiling Point511.7±35.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point263.2±25.9 °C
Exact Mass248.061951
PSA94.56000
LogP0.94
Vapor Pressure0.0±1.3 mmHg at 25°C
Refractive Index1.662
Additional Property<0.1 g/100 mL at 20 ºC

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

Additional Information[1]. Diaz-Ruiz, A., et al., Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats. J Neurosci Res, 2008. 86(15): p. 3410-9. [2]. Begon, E., O. Chosidow, and P. Wolkenstein, [Disulone]. Ann Dermatol Venereol, 2004. 131(12): p. 1062-73.

Customs & Trade Information

HS Code2921590090
Summary2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4,4'-Diaminodiphenylsulfone?

The CAS number of 4,4'-Diaminodiphenylsulfone is 80-08-0.

What are the molecular formula and molecular weight of 4,4'-Diaminodiphenylsulfone?

4,4'-Diaminodiphenylsulfone has molecular formula C12H12N2O2S and molecular weight 248.301 g/mol.

Is 4,4'-Diaminodiphenylsulfone hazardous?

4,4'-Diaminodiphenylsulfone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of 4,4'-Diaminodiphenylsulfone?

For 4,4'-Diaminodiphenylsulfone, Upstream Products: 4-[(4-nitrophenyl)sulfanyl]aniline, Bis(4-nitrophenyl) Sulfone, 4,4'-Dichlorodiphenyl sulfone; Downstream Products: Dapsone hydroxylamine, N-acetyl Dapsone, Bis(4-isothiocyanatophenyl)sulfone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4,4'-Diaminodiphenylsulfone (CAS 80-08-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47595-0 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.