Flumazenil

Also known as: Anexate, Lanexat, Mazicon, Romazicon, Ro 15-1788, RO15-1788, Ro-15-1788, FMZ, YM-684, Flumazepil, Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate, 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

Flumazenil (CAS 78755-81-4) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H14FN3O3 and a molecular weight of 303.288 g/mol. Key properties include a melting point of 201-203°C, a boiling point of 528.0±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 273.1±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 78755-81-4
Jingsj CID: J-15075-8
Molecular Formula: C₁₅H₁₄FN₃O₃
Molecular Weight: 303.288 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	201-203°C
Boiling Point	528.0±50.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	273.1±30.1 °C
Exact Mass	303.101929
PSA	64.43000
LogP	0.67
Appearance	solid \| white
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.634
Storage Conditions	2-8°C
Additional Property	128 mg/L

Activity & Biological Data

Additional Information	[1]. Hoffman EJ, et al. Flumazenil: a benzodiazepine antagonist. Clin Pharm. 1993 Sep;12(9):641-56; quiz 699-701. [2]. Belzung C, et al. Flumazenil induces benzodiazepine partial agonist-like effects in BALB/c but not C57BL/6 mice. Psychopharmacology (Berl). 2000 Jan;148(1):24-32. [3]. Fernandez-Guasti A, et al. Flumazenil blocks the anxiolytic action of allopregnanolone. Eur J Pharmacol. 1995 Jul 25;281(1):113-5. [4]. Loscher W, et al. Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil. Br J Pharmacol. 1994 Dec;113(4):1349-57. [5]. Moy SS, et al. Flumazenil blockade of anxiety following ethanol withdrawal in rats. Psychopharmacology (Berl). 1997 Jun;131(4):354-60.

Additional Information

[1]. Hoffman EJ, et al. Flumazenil: a benzodiazepine antagonist. Clin Pharm. 1993 Sep;12(9):641-56; quiz 699-701. [2]. Belzung C, et al. Flumazenil induces benzodiazepine partial agonist-like effects in BALB/c but not C57BL/6 mice. Psychopharmacology (Berl). 2000 Jan;148(1):24-32. [3]. Fernandez-Guasti A, et al. Flumazenil blocks the anxiolytic action of allopregnanolone. Eur J Pharmacol. 1995 Jul 25;281(1):113-5. [4]. Loscher W, et al. Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil. Br J Pharmacol. 1994 Dec;113(4):1349-57. [5]. Moy SS, et al. Flumazenil blockade of anxiety following ethanol withdrawal in rats. Psychopharmacology (Berl). 1997 Jun;131(4):354-60.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Flumazenil?

The CAS number of Flumazenil is 78755-81-4.

What are the molecular formula and molecular weight of Flumazenil?

Flumazenil has molecular formula C15H14FN3O3 and molecular weight 303.288 g/mol.

What are the upstream and downstream products of Flumazenil?

For Flumazenil, Upstream Products: 1,1,1,3,3,3-Hexamethyldisilazane, N,N-Dimethyl-p-toluidine, Dichloramine; Downstream Products: Flumazenil acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Flumazenil (CAS 78755-81-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15075-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.