Piribedil hydrochloride

吡贝地尔盐酸盐

Also known as: Piribedil monohydrochloride, 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine hydrochloride, 2-(4-Piperonyl-1-piperazinyl)pyrimidine hydrochloride, Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-, hydrochloride (1:1)

Piribedil hydrochloride (CAS 78213-63-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C16H19ClN4O2 and a molecular weight of 334.80100 g/mol. It is also known as Piribedil monohydrochloride, 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine hydrochloride and 2-(4-Piperonyl-1-piperazinyl)pyrimidine hydrochloride. Key properties include a boiling point of 469.4ºC at 760 mmHg and a flash point of 237.7ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 78213-63-5
Jingsj CID: J-1959859-6
Molecular Formula: C₁₆H₁₉ClN₄O₂
Chinese Name: 吡贝地尔盐酸盐
Molecular Weight: 334.80100 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	469.4ºC at 760 mmHg
Flash Point	237.7ºC
Exact Mass	334.12000
PSA	50.72000
LogP	2.33240

Activity & Biological Data

Target	D2 Receptor D3 Receptor
Additional Information	[1]. Sweet RD, et al. Piribedil, a dopamine agonist, in Parkinson's disease. Clin Pharmacol Ther. 1974 Dec;16(6):1077-82. [2]. Gerlach M, et al. The effect of piribedil on L-DOPA-induced dyskinesias in a rat model of Parkinson's disease: differential role of α(2) adrenergic mechanisms. J Neural Transm (Vienna). 2013 Jan;120(1):31-6. [3]. Smith LA, Tet al. Repeated administration of piribedil induces less dyskinesia than L-dopa in MPTP-treated common marmosets: a behavioural and biochemical investigation. Mov Disord. 2002 Sep;17(5):887-901. [4]. Xiong Zhang, et al. Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis. Cancer Lett. 2018 Sep 1;431:150-160.

Target

D2 Receptor D3 Receptor

Additional Information

[1]. Sweet RD, et al. Piribedil, a dopamine agonist, in Parkinson's disease. Clin Pharmacol Ther. 1974 Dec;16(6):1077-82. [2]. Gerlach M, et al. The effect of piribedil on L-DOPA-induced dyskinesias in a rat model of Parkinson's disease: differential role of α(2) adrenergic mechanisms. J Neural Transm (Vienna). 2013 Jan;120(1):31-6. [3]. Smith LA, Tet al. Repeated administration of piribedil induces less dyskinesia than L-dopa in MPTP-treated common marmosets: a behavioural and biochemical investigation. Mov Disord. 2002 Sep;17(5):887-901. [4]. Xiong Zhang, et al. Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis. Cancer Lett. 2018 Sep 1;431:150-160.

Frequently Asked Questions

What is the CAS number of Piribedil hydrochloride?

The CAS number of Piribedil hydrochloride is 78213-63-5.

What are the molecular formula and molecular weight of Piribedil hydrochloride?

Piribedil hydrochloride has molecular formula C16H19ClN4O2 and molecular weight 334.80100 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Piribedil hydrochloride (CAS 78213-63-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959859-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.