Methylene Blue trihydrate
Also known as: Basic Blue 9 trihydrate, C.I. 52015 trihydrate, 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate, Methylthioninium chloride trihydrate, Tetramethylthionine chloride trihydrate, Methylene Blue hydrate, Methylene Blue, CP
Methylene Blue trihydrate (CAS 7220-79-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H24ClN3O3S and a molecular weight of 373.898 g/mol. Key properties include a melting point of 190 °C (dec.)(lit.), a density of 0.98 g/mL at 25 °C and a flash point of 14 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour and H319 — Causes serious eye irritation. It is listed by 2 suppliers, 1 of which publish reference prices, from 0.88 to 10.40 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 7220-79-3
- Jingsj CID
- J-1114822-9
- Molecular Formula
- C16H24ClN3O3S
- Molecular Weight
- 373.898 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | IND 25g | ¥22.00 | $0.13 /gBest ¥0.88/g CNY | CN China MOQ 25g | |
In Stock | 100X DNA STAIN 25ml | ¥260.00 | $1.56 /ml ¥10.40/ml CNY | CN China MOQ 25ml | |
Made to Order | - | - | CN China |
Physicochemical Properties
| Melting Point | 190 °C (dec.)(lit.) |
|---|---|
| Density | 0.98 g/mL at 25 °C |
| Flash Point | 14 °C |
| Exact Mass | 373.122681 |
| PSA | 75.07000 |
| Additional Property | 4 g/100 mL |
GHS Safety & Compliance
- H225 — Highly flammable liquid and vapour
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | Guanylyl cyclase (sGC)[1]. Monoamine oxidase A (MAO-A)[1]. NO synthase (NOS)[1] |
|---|---|
| Additional Information | [1]. Delport A, et al. Methylene blue and its analogues as antidepressant compounds. Metab Brain Dis. 2017 Oct;32(5):1357-1382. [2]. Masaki E, et al. Methylene blue, a soluble guanylyl cyclase inhibitor, reduces the sevoflurane minimum alveolar anesthetic concentration and decreases the brain cyclic guanosine monophosphate content in rats. Anesth Analg. 1999 Aug;89(2):484-9. [3]. McCartney SL, et al. Intraoperative vasoplegia: methylene blue to the rescue! Curr Opin Anaesthesiol. 2018 Feb;31(1):43-49. |
Frequently Asked Questions
What is the CAS number of Methylene Blue trihydrate?
The CAS number of Methylene Blue trihydrate is 7220-79-3.
What are the molecular formula and molecular weight of Methylene Blue trihydrate?
Methylene Blue trihydrate has molecular formula C16H24ClN3O3S and molecular weight 373.898 g/mol.
Which suppliers offer Methylene Blue trihydrate?
2 supplier(s) listed; reference unit price ¥0.88–10.40 /g.
Is Methylene Blue trihydrate hazardous?
Methylene Blue trihydrate has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H319 — Causes serious eye irritation.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Methylene Blue trihydrate (CAS 7220-79-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1114822-9 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.