Curcumin
Also known as: Natural Yellow 3, Diferuloylmethane, Turmeric yellow, C.I. 75300, C.I. Natural Yellow 3, (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferulylmethane, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Gelbwurz, Halad, Haldar, Curcuma, Souchet
Curcumin (CAS 458-37-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H20O6 and a molecular weight of 368.380 g/mol. Key properties include a melting point of 183 °C, a boiling point of 593.2±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 209.7±23.6 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. It is listed by 2 suppliers, 1 of which publish reference prices, from 3.95 to 17.00 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 458-37-7
- Jingsj CID
- J-19181-0
- Molecular Formula
- C21H20O6
- Molecular Weight
- 368.380 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | 分析标准品，≥95% 20mg | ¥79.00 | $0.59 /mgBest ¥3.95/mg CNY | CN China MOQ 20mg | |
In Stock | 98% 100g | ¥785.00 | $1.17 /g ¥7.85/g CNY | CN China MOQ 100g | |
In Stock | 98% 25g | ¥210.00 | $1.26 /g ¥8.40/g CNY | CN China MOQ 25g |
Physicochemical Properties
| Melting Point | 183 °C |
|---|---|
| Boiling Point | 593.2±50.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 209.7±23.6 °C |
| Exact Mass | 368.125977 |
| PSA | 96.22000 |
| LogP | 2.85 |
| Additional Property | 13 (vs air) |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.672 |
| Additional Property | Slightly soluble (hot) |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Keap1-Nrf2[1], Histone acetyltransferase[6] |
|---|---|
| Additional Information | [1]. Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004 [2]. Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53. [3]. Cao A, et all. Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress. Apoptosis. 2013 Jul 24. [Epub ahead of print] [4]. Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4. [5]. Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4. [6]. Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303. |
Customs & Trade Information
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Curcumin?
The CAS number of Curcumin is 458-37-7.
What are the molecular formula and molecular weight of Curcumin?
Curcumin has molecular formula C21H20O6 and molecular weight 368.380 g/mol.
Which suppliers offer Curcumin?
2 supplier(s) listed; reference unit price ¥3.95–17.00 /mg.
Is Curcumin hazardous?
Curcumin has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Curcumin?
For Curcumin, Upstream Products: Vanillin, 2,4-Pentanedione, 4-Hydroxybenzaldehyde; Downstream Products: Tetrahydrocurcumin, Hexahydrocurcumin, Octahydrocurcumin.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Curcumin (CAS 458-37-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19181-0 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.