Forskolin

Also known as: Coleonol, Colforsin, ForsLean, HL 362, L 75-1362B, 7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxy-labd-14-en-11-one, 7beta-Acetoxy-1alpha,6beta,9alpha-trihydroxy-8,13-epoxy-labd-14-en-11-one

Forskolin (CAS 66575-29-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H34O7 and a molecular weight of 410.501 g/mol. Key properties include a melting point of 282-232ºC, a boiling point of 519.9±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 171.8±23.6 °C. It is classified under GHS with signal word Warning and hazard statements H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 66575-29-9
Jingsj CID: J-15190-6
Molecular Formula: C₂₂H₃₄O₇
Molecular Weight: 410.501 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	282-232ºC
Boiling Point	519.9±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	171.8±23.6 °C
Exact Mass	410.230438
PSA	113.29000
LogP	3.40
Vapor Pressure	0.0±3.1 mmHg at 25°C
Refractive Index	1.552

GHS Safety & Compliance

IrritantSignal word: Warning

H312 — Harmful in contact with skin

Activity & Biological Data

Target	IC50: 41 nM (Adenylyl cyclase)[1] EC50: 0.5 μM (Adenylyl cyclase)[1]
Additional Information	[1]. Robbins JD, et al. Forskolin carbamates: binding and activation studies with type I adenylyl cyclase. J Med Chem. 1996 Jul 5;39(14):2745-52. [2]. Rodriguez G, et al. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. J Biol Chem. 2013 Mar 8;288(10):7137-46. [3]. Matsumiya W, et al. Forskolin modifies retinal vascular development in Mrp4-knockout mice. Invest Ophthalmol Vis Sci. 2012 Dec 7;53(13):8029-35. [4]. Ríos-Silva M, et al. Effect of chronic administration of forskolin on glycemia and oxidative stress in rats with and without experimental diabetes. Int J Med Sci. 2014 Mar 11;11(5):448-52.

Target

IC50: 41 nM (Adenylyl cyclase)[1] EC50: 0.5 μM (Adenylyl cyclase)[1]

Additional Information

[1]. Robbins JD, et al. Forskolin carbamates: binding and activation studies with type I adenylyl cyclase. J Med Chem. 1996 Jul 5;39(14):2745-52. [2]. Rodriguez G, et al. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. J Biol Chem. 2013 Mar 8;288(10):7137-46. [3]. Matsumiya W, et al. Forskolin modifies retinal vascular development in Mrp4-knockout mice. Invest Ophthalmol Vis Sci. 2012 Dec 7;53(13):8029-35. [4]. Ríos-Silva M, et al. Effect of chronic administration of forskolin on glycemia and oxidative stress in rats with and without experimental diabetes. Int J Med Sci. 2014 Mar 11;11(5):448-52.

Frequently Asked Questions

What is the CAS number of Forskolin?

The CAS number of Forskolin is 66575-29-9.

What are the molecular formula and molecular weight of Forskolin?

Forskolin has molecular formula C22H34O7 and molecular weight 410.501 g/mol.

Is Forskolin hazardous?

Forskolin has GHS signal word Warning and hazard statements H312 — Harmful in contact with skin.

What are the upstream and downstream products of Forskolin?

For Forskolin, Downstream Products: Forskolin J.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Forskolin (CAS 66575-29-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15190-6 (accessed 2026-10-30).

Data for reference only; verify product details with suppliers before purchase.