Diosgenin

Also known as: (25R)-Spirost-5-en-3β-ol, 3β-Hydroxy-5-spirostene, Nitogenin, (25R)-5-Spirosten-3β-ol, Spirost-5-en-3β-ol, (25R)-

Diosgenin (CAS 512-04-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C27H42O3 and a molecular weight of 414.621 g/mol. Key properties include a melting point of 205-208°C, a boiling point of 527.1±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 272.6±30.1 °C. It is listed by 1 supplier, from 7.50 to 44.00 CNY. Record last updated Aug 21, 2026.

CAS No.: 512-04-9
Jingsj CID: J-18850-2
Molecular Formula: C₂₇H₄₂O₃
Molecular Weight: 414.621 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Jingkang In Stock	分析标准品 20mg	¥150.00	$1.12 /mgBest ¥7.50/mg CNY	CN China MOQ 20mg	Visit Website
Jingkang In Stock	90% 100g	¥3,000.00	$4.49 /g ¥30.00/g CNY	CN China MOQ 100g	Visit Website
Jingkang In Stock	90% 25g	¥800.00	$4.79 /g ¥32.00/g CNY	CN China MOQ 25g	Visit Website
Jingkang In Stock	90% 5g	¥220.00	$6.58 /g ¥44.00/g CNY	CN China MOQ 5g	Visit Website

Physicochemical Properties

Melting Point	205-208°C
Boiling Point	527.1±50.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	272.6±30.1 °C
Exact Mass	414.313385
PSA	38.69000
LogP	5.84
Vapor Pressure	0.0±3.1 mmHg at 25°C
Refractive Index	1.564
Additional Property	chloroform: 20 mg/mL, clear, slightly yellow

Activity & Biological Data

Target	STAT3
Additional Information	[1]. Jeremy E. Chojnacki, et al. Bivalent ligands incorporating curcumin and diosgenin asmultifunctional compounds against Alzheimer’s disease. Bioorganic & Medicinal Chemistry, 23 (2015) 7324–7331 [2]. Li F, et al. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Lett. 2010 Jun 28;292(2):197-207. [3]. Wang X, et al. Effect of diosgenin on metabolic dysfunction: Role of ERβ in the regulation of PPARγ. Toxicol Appl Pharmacol. 2015 Dec 1;289(2):286-96.

Target

STAT3

Additional Information

[1]. Jeremy E. Chojnacki, et al. Bivalent ligands incorporating curcumin and diosgenin asmultifunctional compounds against Alzheimer’s disease. Bioorganic & Medicinal Chemistry, 23 (2015) 7324–7331 [2]. Li F, et al. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Lett. 2010 Jun 28;292(2):197-207. [3]. Wang X, et al. Effect of diosgenin on metabolic dysfunction: Role of ERβ in the regulation of PPARγ. Toxicol Appl Pharmacol. 2015 Dec 1;289(2):286-96.

Customs & Trade Information

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Diosgenin?

The CAS number of Diosgenin is 512-04-9.

What are the molecular formula and molecular weight of Diosgenin?

Diosgenin has molecular formula C27H42O3 and molecular weight 414.621 g/mol.

Which suppliers offer Diosgenin?

1 supplier(s) listed; reference unit price ¥7.50–44.00 /mg.

What are the upstream and downstream products of Diosgenin?

For Diosgenin, Upstream Products: Trillin, Yamogenin, Kryptogenin; Downstream Products: Polyphyllin I, Cholesterol, Dehydroepiandrosterone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Diosgenin (CAS 512-04-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18850-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.