2-Chloro-6-(piperazin-1-yl)pyrazine
Also known as: MK 212, 6-Chloro-2-(1-piperazinyl)pyrazine, 1-(6-Chloro-2-pyrazinyl)piperazine, 4-(6-Chloro-2-pyrazinyl)piperazine, 2-Chloro-6-(1-piperazinyl)pyrazine, CPP, NSC 317326
2-Chloro-6-(piperazin-1-yl)pyrazine (CAS 64022-27-1) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H11ClN4 and a molecular weight of 198.65700 g/mol. Key properties include a boiling point of 215.2±23.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 83.9±22.6 °C. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.
- CAS No.
- 64022-27-1
- Jingsj CID
- J-28118-0
- Molecular Formula
- C8H11ClN4
- Molecular Weight
- 198.65700 g/mol
- Category
- Organohalogen Compounds
- Last updated
- 11/2/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 215.2±23.0 °C at 760 mmHg |
|---|---|
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 83.9±22.6 °C |
| Exact Mass | 103.063332 |
| PSA | 41.05000 |
| LogP | -0.15 |
| Vapor Pressure | 0.1±0.9 mmHg at 25°C |
| Refractive Index | 1.462 |
| Storage Conditions | 2-8°C |
Activity & Biological Data
| Target | 5-HT1C Receptor 5-HT2 Receptor |
|---|---|
| Additional Information | [1]. Lee HS, et, al. Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol Psychiatry. 1992 Mar 1;31(5):460-70. [2]. Conn PJ, et, al. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther. 1987 Aug;242(2):552-7. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 2-Chloro-6-(piperazin-1-yl)pyrazine?
The CAS number of 2-Chloro-6-(piperazin-1-yl)pyrazine is 64022-27-1.
What are the molecular formula and molecular weight of 2-Chloro-6-(piperazin-1-yl)pyrazine?
2-Chloro-6-(piperazin-1-yl)pyrazine has molecular formula C8H11ClN4 and molecular weight 198.65700 g/mol.
What are the upstream and downstream products of 2-Chloro-6-(piperazin-1-yl)pyrazine?
For 2-Chloro-6-(piperazin-1-yl)pyrazine, Upstream Products: tert-Butyl 4-(6-chloropyrazin-2-yl)piperazine-1-carboxylate, Piperazine, 2,6-Dichloropyrazine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Chloro-6-(piperazin-1-yl)pyrazine (CAS 64022-27-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28118-0 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.