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Piperazine

Also known as: 1,4-DIAZACYCLOHEXANE, 1,4-DIAZACYCLOHEXANE, CERTIFIED REFERENCE MATERIAL, 1,4-Diazacyclohexan, 1,4-Diazacyclohexane,Diethylenediamine, 1,4-diazacyclohexane, 1,4-piperazine, AKOS 90646, AKOS BBS-00004315, Anhydrous Piperazine (PIP), DIETHYLENEDIAMINE, Diethylenediamine, EINECS 203-808-3, HEXAHYDRO-1,4-DIAZINE, HEXAHYDROPYRAZINE, Hexahydropyrazine, MFCD00005953, PIPERAZINE, PIPERAZINE CHIPS, Pyrazine hexahydride, Trimetazidine Hydrochloride Impurity G

Piperazine (CAS 110-85-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C4H10N2 and a molecular weight of 86.136 g/mol. Key properties include a melting point of 109-112 °C(lit.), a boiling point of 149.3±8.0 °C at 760 mmHg, a density of 0.9±0.1 g/cm3 and a flash point of 49.7±10.2 °C. It is classified under GHS with signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage, H317 — May cause an allergic skin reaction and H334 — May cause allergy or asthma symptoms if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
110-85-0
Jingsj CID
J-33662-0
Molecular Formula
C4H10N2
Molecular Weight
86.136 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point109-112 °C(lit.)
Boiling Point149.3±8.0 °C at 760 mmHg
Density0.9±0.1 g/cm3
Flash Point49.7±10.2 °C
Exact Mass86.084396
PSA24.06000
LogP-1.17
Vapor Pressure4.0±0.3 mmHg at 25°C
Refractive Index1.424
Additional Property150 g/L (20 ºC)

GHS Safety & Compliance

Corrosion / Health HazardSignal word: Danger
  • H314 — Causes severe skin burns and eye damage
  • H317 — May cause an allergic skin reaction
  • H334 — May cause allergy or asthma symptoms if inhaled

Activity & Biological Data

Additional Information[1]. Racz PI, et al. Application of Caenorhabditis elegans (nematode) and Danio rerio embryo (zebrafish) as model systems to screen for developmental and reproductive toxicity of Piperazine compounds. Toxicol In Vitro. 2017 Oct;44:11-16. [2]. Stowe HM, et al. First-principles assessment of CO2 capture mechanisms in aqueous piperazine solution. Phys Chem Chem Phys. 2016 Sep 14;18(36):25296-25307.

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Piperazine?

The CAS number of Piperazine is 110-85-0.

What are the molecular formula and molecular weight of Piperazine?

Piperazine has molecular formula C4H10N2 and molecular weight 86.136 g/mol.

Is Piperazine hazardous?

Piperazine has GHS signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage; H317 — May cause an allergic skin reaction; H334 — May cause allergy or asthma symptoms if inhaled.

What are the upstream and downstream products of Piperazine?

For Piperazine, Upstream Products: Iminodiacetonitrile, Ethylene glycol, Ethylene oxide; Downstream Products: 4,6-Dimethoxy-2-(piperazin-1-yl)pyrimidine, Methyl 2-(piperazin-1-yl)nicotinate, 5-piperazin-1-ylisoquinoline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Piperazine (CAS 110-85-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33662-0 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.