N-Acetyl-L-cysteine

Also known as: Acetylcysteine, N-Acetylcysteine, N-Acetyl-L-cysteine, N-acetyl-cysteine, Ac-Cys-OH, N-Alpha-acetyl-L-cysteine, L-N-acetyl-cysteine, N-acetyl-3-mercaptoalanine

N-Acetyl-L-cysteine (CAS 616-91-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H9NO3S and a molecular weight of 163.195 g/mol. Key properties include a melting point of 106-108 °C(lit.), a boiling point of 407.7±40.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 200.4±27.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 616-91-1
Jingsj CID: J-9017-7
Molecular Formula: C₅H₉NO₃S
Molecular Weight: 163.195 g/mol
Category: Organic Acids
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	106-108 °C(lit.)
Boiling Point	407.7±40.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	200.4±27.3 °C
Exact Mass	163.030319
PSA	105.20000
LogP	-0.15
Vapor Pressure	0.0±2.0 mmHg at 25°C
Refractive Index	1.519

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Kalimeris K, et al. N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion. J Surg Res. 2016 Dec;206(2):263-272 [2]. Ferrari G, et al. N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci. 1995 Apr;15(4):2857-66. [3]. Tsai JC, et al. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem. 1996 Feb 16;271(7):3667-70. [4]. Yan CY, et al. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci. 1998 Jun 1;18(11):4042-9. [5]. Farr SA, et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 2003 Mar;84(5):1173-83.

Target

Human Endogenous Metabolite

Additional Information

[1]. Kalimeris K, et al. N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion. J Surg Res. 2016 Dec;206(2):263-272 [2]. Ferrari G, et al. N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci. 1995 Apr;15(4):2857-66. [3]. Tsai JC, et al. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem. 1996 Feb 16;271(7):3667-70. [4]. Yan CY, et al. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci. 1998 Jun 1;18(11):4042-9. [5]. Farr SA, et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 2003 Mar;84(5):1173-83.

Customs & Trade Information

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of N-Acetyl-L-cysteine?

The CAS number of N-Acetyl-L-cysteine is 616-91-1.

What are the molecular formula and molecular weight of N-Acetyl-L-cysteine?

N-Acetyl-L-cysteine has molecular formula C5H9NO3S and molecular weight 163.195 g/mol.

What are the upstream and downstream products of N-Acetyl-L-cysteine?

For N-Acetyl-L-cysteine, Upstream Products: L-Cystine, Isopropenyl acetate, L-Cysteine; Downstream Products: L-Cystathionine, N,N'-Diacetyl-L-cystine, 4-tert-butylbenzamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "N-Acetyl-L-cysteine (CAS 616-91-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-9017-7 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.