trans-Chalcone

Also known as: (E)-Chalcone, Benzalacetophenone, Benzylideneacetophenone, 1,3-Diphenyl-2-propen-1-one, (E)-1,3-diphenylprop-2-en-1-one, Phenyl styryl ketone, Phenyl (E)-2-phenylethenyl ketone, 2-Benzalacetophenone, 2-Benzylideneacetophenone, 3-Phenylacrylophenone, β-Benzoylstyrene, β-Phenylacrylophenone, trans-Benzalacetophenone, trans-Benzylideneacetophenone, (2E)-1,3-diphenylprop-2-en-1-one

trans-Chalcone (CAS 614-47-1) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C15H12O and a molecular weight of 208.255 g/mol. Key properties include a melting point of 55-57ºC, a boiling point of 346.6±25.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 150.1±18.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 614-47-1
Jingsj CID: J-25375-2
Molecular Formula: C₁₅H₁₂O
Molecular Weight: 208.255 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	55-57ºC
Boiling Point	346.6±25.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	150.1±18.1 °C
Exact Mass	208.088821
PSA	17.07000
LogP	4.01
Vapor Pressure	0.0±0.8 mmHg at 25°C
Refractive Index	1.625

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information	[1]. Luis Felipe Buso Bortolotto, et al. Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest. Biomed Pharmacother. 2017 Jan;85:425-433. [2]. Mahmoud Najafian, et al. Trans-chalcone: a novel small molecule inhibitor of mammalian alpha-amylase. Mol Biol Rep. 2011 Mar;38(3):1617-20. [3]. Tamires Aparecida Bitencourt, et al. Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum. BMC Complement Altern Med. 2013 Sep 17;13:229.

Additional Information

[1]. Luis Felipe Buso Bortolotto, et al. Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest. Biomed Pharmacother. 2017 Jan;85:425-433. [2]. Mahmoud Najafian, et al. Trans-chalcone: a novel small molecule inhibitor of mammalian alpha-amylase. Mol Biol Rep. 2011 Mar;38(3):1617-20. [3]. Tamires Aparecida Bitencourt, et al. Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum. BMC Complement Altern Med. 2013 Sep 17;13:229.

Frequently Asked Questions

What is the CAS number of trans-Chalcone?

The CAS number of trans-Chalcone is 614-47-1.

What are the molecular formula and molecular weight of trans-Chalcone?

trans-Chalcone has molecular formula C15H12O and molecular weight 208.255 g/mol.

Is trans-Chalcone hazardous?

trans-Chalcone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of trans-Chalcone?

For trans-Chalcone, Upstream Products: 2,3-Dibromo-1,3-diphenyl-1-propanone, Cinnamoyl chloride, Phenylboronic acid; Downstream Products: N,N'-Diacetylhydrazine, Ethyl benzoate, Benzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "trans-Chalcone (CAS 614-47-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25375-2 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.