Manool

Also known as: Manool, (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol, [1S-[1α(S*),4aβ,8aα]]-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol, 5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol, Labda-8(20),14-dien-13-ol, (13R)-, MFCD01310996, NSC 165961

Manool (CAS 596-85-0) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C20H34O and a molecular weight of 290.48300 g/mol. Key properties include a melting point of 49-52ºC(lit.), a boiling point of 368.2ºC at 760mmHg, a density of 0.93g/cm3 and a flash point of 118.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 596-85-0
Jingsj CID: J-18873-7
Molecular Formula: C₂₀H₃₄O
Molecular Weight: 290.48300 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	49-52ºC(lit.)
Boiling Point	368.2ºC at 760mmHg
Density	0.93g/cm3
Flash Point	118.2ºC
Exact Mass	290.26100
PSA	20.23000
LogP	5.50240
Refractive Index	1.5

Activity & Biological Data

Additional Information	[1]. de Oliveira PF, et al. Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells. Cytotechnology. 2016;68(5):2139-2143. [2]. Pratsinis H, et al. Antiproliferative activity of Greek propolis. J Med Food. 2010;13(2):286-290. [3]. Nicolella HD, et al. Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. Food Chem Toxicol. 2014;72:8-12.

Additional Information

[1]. de Oliveira PF, et al. Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells. Cytotechnology. 2016;68(5):2139-2143. [2]. Pratsinis H, et al. Antiproliferative activity of Greek propolis. J Med Food. 2010;13(2):286-290. [3]. Nicolella HD, et al. Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. Food Chem Toxicol. 2014;72:8-12.

Frequently Asked Questions

What is the CAS number of Manool?

The CAS number of Manool is 596-85-0.

What are the molecular formula and molecular weight of Manool?

Manool has molecular formula C20H34O and molecular weight 290.48300 g/mol.

What are the upstream and downstream products of Manool?

For Manool, Upstream Products: Geranylgeranyl pyrophosphate triammonium salt, Sclareol, acetic acid; Downstream Products: (1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthaleneacetaldehyde, Totarol, Sclareol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Manool (CAS 596-85-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18873-7 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.