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D-erythro-Sphingosine

Also known as: Sphingosine, D-Sphingosine, D-erythro-Sphingosine, D-erythrosphingosine, (2S,3R,4E)-2-Aminooctadec-4-ene-1,3-diol, (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol, (2S,3R,E)-2-Amino-4-octadecene-1,3-diol, 4-Sphingenine, trans-4-Sphingenine, (4E)-sphingenine, (4E)-sphing-4-enine, C18-Sphingosine, trans-D-erythro-sphingosine, SPHINGOSINE, C18 CHAIN, SPHINGOSINE, D-ERYTHRO, EINECS 204-651-3, UNII:0Y6SVQ612Q, MFCD00036751

D-erythro-Sphingosine (CAS 123-78-4) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C18H37NO2 and a molecular weight of 299.492 g/mol. Key properties include a melting point of 81-82ºC, a boiling point of 445.9±45.0 °C at 760 mmHg, a density of 0.9±0.1 g/cm3 and a flash point of 223.5±28.7 °C. It is listed by 1 supplier; request a quote for pricing. Record last updated Aug 21, 2026.

CAS No.
123-78-4
Jingsj CID
J-48487-1
Molecular Formula
C18H37NO2
Molecular Weight
299.492 g/mol
Category
Alcohols
Last updated
8/21/2026
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Physicochemical Properties

Melting Point81-82ºC
Boiling Point445.9±45.0 °C at 760 mmHg
Density0.9±0.1 g/cm3
Flash Point223.5±28.7 °C
Exact Mass299.282440
PSA66.48000
LogP6.40
Vapor Pressure0.0±2.4 mmHg at 25°C
Refractive Index1.489
Additional Propertychloroform: 20 mg/mL

Activity & Biological Data

Targetp32:8 μM (EC50) PKC Human Endogenous Metabolite
Additional Information[1]. Pushkareva MYu, et al. Regulation of sphingosine-activated protein kinases: selectivity of activation by sphingoid basesand inhibition by non-esterified fatty acids. Biochem J. 1993 Sep 15;294 ( Pt 3):699-703. [2]. Khan WA, et al. Protein kinase C and platelet inhibition by D-erythro-Sphingosine: comparison with N,N-dimethylsphingosine and commercial preparation. Biochem Biophys Res Commun. 1990 Oct 30;172(2):683-91. [3]. Pham VT, et al. A concise synthesis of a promising protein kinase C inhibitor: D-erythro-Sphingosine. Arch Pharm Res. 2007 Jan;30(1):22-7.

Customs & Trade Information

HS Code2922199090
Summary2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of D-erythro-Sphingosine?

The CAS number of D-erythro-Sphingosine is 123-78-4.

What are the molecular formula and molecular weight of D-erythro-Sphingosine?

D-erythro-Sphingosine has molecular formula C18H37NO2 and molecular weight 299.492 g/mol.

Which suppliers offer D-erythro-Sphingosine?

1 supplier(s) listed; request a quote for pricing.

What are the upstream and downstream products of D-erythro-Sphingosine?

For D-erythro-Sphingosine, Upstream Products: (2S,3R,4E)-2-azido-4-octadecene-1,3-diol; Downstream Products: N-acetylsphingosine, D-erythro-Sphingosine, Sphingosine 1-phosphate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "D-erythro-Sphingosine (CAS 123-78-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48487-1 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.