7-Hydroxymethotrexate
7-羟基甲氨蝶呤
Also known as: 7-Hydroxy Methotrexate, 7-hydroxy methotrexate, Methotrexate 7-Hydroxy Metabolite, NSC 380962
7-Hydroxymethotrexate (CAS 5939-37-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H22N8O6 and a molecular weight of 470.43900 g/mol. It is also known as 7-Hydroxy Methotrexate, 7-hydroxy methotrexate and Methotrexate 7-Hydroxy Metabolite. Key properties include a melting point of 230ºC dec. and a density of 1.68g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 5939-37-7
- Jingsj CID
- J-899555-1
- Molecular Formula
- C20H22N8O6
- Chinese Name
- 7-羟基甲氨蝶呤
- Molecular Weight
- 470.43900 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 230ºC dec. |
|---|---|
| Density | 1.68g/cm3 |
| Exact Mass | 470.16600 |
| PSA | 230.77000 |
| LogP | 1.52730 |
| Refractive Index | 1.76 |
Activity & Biological Data
| Additional Information | [1]. L Fahrig, et al. Pharmacokinetics of methotrexate (MTX) and 7-hydroxymethotrexate (7-OH-MTX) in rats and evidence for the metabolism of MTX to 7-OH-MTX. Cancer Chemother Pharmacol. 1989;23(3):156-60. [2]. Ping Guo, et al. Determination of methotrexate and its major metabolite 7-hydroxymethotrexate in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2007 Apr 11;43(5):1789-95. |
|---|
Frequently Asked Questions
What is the CAS number of 7-Hydroxymethotrexate?
The CAS number of 7-Hydroxymethotrexate is 5939-37-7.
What are the molecular formula and molecular weight of 7-Hydroxymethotrexate?
7-Hydroxymethotrexate has molecular formula C20H22N8O6 and molecular weight 470.43900 g/mol.
What are the upstream and downstream products of 7-Hydroxymethotrexate?
For 7-Hydroxymethotrexate, Upstream Products: Methotrexate dimethyl ester, DL-Methotrexate.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "7-Hydroxymethotrexate (CAS 5939-37-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-899555-1 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.