Idarubicin

伊达比星

Also known as: 4-Demethoxydaunorubicin, 4-Demethoxydaunomycin, Idamycin, Idarubicina, Idarubicine, Idarubicinum, 4-Demethoxy-daunorubicin, (7S,9S)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Idarubicin (CAS 58957-92-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H27NO9 and a molecular weight of 497.494 g/mol. It is also known as 4-Demethoxydaunorubicin, 4-Demethoxydaunomycin and Idamycin. Key properties include a boiling point of 725.4±60.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 392.5±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 58957-92-9
Jingsj CID: J-42086-0
Molecular Formula: C₂₆H₂₇NO₉
Chinese Name: 伊达比星
Molecular Weight: 497.494 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	725.4±60.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	392.5±32.9 °C
Exact Mass	497.168579
PSA	176.61000
LogP	2.95
Appearance	solid
Vapor Pressure	0.0±2.5 mmHg at 25°C
Refractive Index	1.706
Storage Conditions	2-8°C

Activity & Biological Data

Target	Topoisomerase II
Additional Information	[1]. Orlandi P, et al. Idarubicin and idarubicinol effects on breast cancer multicellular spheroids. J Chemother. 2005 Dec;17(6):663-7. [2]. Robert J. Clinical pharmacokinetics of idarubicin. Clin Pharmacokinet. 1993 Apr;24(4):275-88. [3]. Siegsmund MJ, et al. Enhanced in vitro cytotoxicity of idarubicin compared to epirubicin and doxorubicin in rat prostate carcinoma cells. Eur Urol. 1997;31(3):365-70. [4]. Gewirtz DA, et al. Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line. Cancer Chemother Pharmacol. 1998;41(5):361- [5]. Kinnunen U, et al. Idarubicin inhibits the growth of bacteria and yeasts in an automated blood culture system. Eur J Clin Microbiol Infect Dis. 2009 Mar;28(3):301-3.

Target

Topoisomerase II

Additional Information

[1]. Orlandi P, et al. Idarubicin and idarubicinol effects on breast cancer multicellular spheroids. J Chemother. 2005 Dec;17(6):663-7. [2]. Robert J. Clinical pharmacokinetics of idarubicin. Clin Pharmacokinet. 1993 Apr;24(4):275-88. [3]. Siegsmund MJ, et al. Enhanced in vitro cytotoxicity of idarubicin compared to epirubicin and doxorubicin in rat prostate carcinoma cells. Eur Urol. 1997;31(3):365-70. [4]. Gewirtz DA, et al. Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line. Cancer Chemother Pharmacol. 1998;41(5):361- [5]. Kinnunen U, et al. Idarubicin inhibits the growth of bacteria and yeasts in an automated blood culture system. Eur J Clin Microbiol Infect Dis. 2009 Mar;28(3):301-3.

Frequently Asked Questions

What is the CAS number of Idarubicin?

The CAS number of Idarubicin is 58957-92-9.

What are the molecular formula and molecular weight of Idarubicin?

Idarubicin has molecular formula C26H27NO9 and molecular weight 497.494 g/mol.

What are the upstream and downstream products of Idarubicin?

For Idarubicin, Upstream Products: Daunorubicin hydrochloride, Idarubicinone.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Idarubicin (CAS 58957-92-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42086-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.