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Hydrochlorothiazide

Also known as: HCTZ, HCT, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, Esidrix, Hydrodiuril, Oretic, Dichlotride, Aquazide H

Hydrochlorothiazide (CAS 58-93-5) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C7H8ClN3O4S2 and a molecular weight of 297.739 g/mol. Key properties include a melting point of 273 °C, a boiling point of 577.0±60.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 302.7±32.9 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
58-93-5
Jingsj CID
J-37945-8
Molecular Formula
C7H8ClN3O4S2
Molecular Weight
297.739 g/mol
Category
Organohalogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point273 °C
Boiling Point577.0±60.0 °C at 760 mmHg
Density1.7±0.1 g/cm3
Flash Point302.7±32.9 °C
Exact Mass296.964478
PSA135.12000
LogP-0.07
Vapor Pressure0.0±1.6 mmHg at 25°C
Refractive Index1.632
StabilityStable. Incompatible with strong oxidizing agents.

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

Additional Information[1]. Duarte, J.D. and R.M. Cooper-DeHoff, Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther, 2010. 8(6): p. 793-802.

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Hydrochlorothiazide?

The CAS number of Hydrochlorothiazide is 58-93-5.

What are the molecular formula and molecular weight of Hydrochlorothiazide?

Hydrochlorothiazide has molecular formula C7H8ClN3O4S2 and molecular weight 297.739 g/mol.

Is Hydrochlorothiazide hazardous?

Hydrochlorothiazide has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Hydrochlorothiazide?

For Hydrochlorothiazide, Upstream Products: 4-Amino-6-chlorobenzene-1,3-disulfonamide, Formaldehyde, Chlorothiazide; Downstream Products: 4-Amino-6-chlorobenzene-1,3-disulfonamide, Formaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Hydrochlorothiazide (CAS 58-93-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37945-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.